A novel hybrid SCCmec-mecC region in Staphylococcus sciuri
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Methicillin resistance in Staphylococcus spp. results from the expression of an alternative penicillin-binding protein 2a (encoded by mecA) with a low affinity for β-lactam antibiotics. Recently, a novel variant of mecA known as mecC (formerly mecALGA251) was identified in Staphylococcus aureus isolates from both humans and animals. In this study, we identified two Staphylococcus sciuri subsp. carnaticus isolates from bovine infections that harbour three different mecA homologues: mecA, mecA1 and mecC.
Harrison , E M , Paterson , G K , Holden , M T G , Ba , X , Rolo , J , Morgan , F J E , Pichon , B , Kearns , A , Zadoks , R N , Peacock , S J , Parkhill , J & Holmes , M A 2014 , ' A novel hybrid SCC mec - mecC region in Staphylococcus sciuri ' Journal of Antimicrobial Chemotherapy , vol 69 , no. 4 , pp. 911-918 . DOI: 10.1093/jac/dkt452
Journal of Antimicrobial Chemotherapy
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