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A novel hybrid SCCmec-mecC region in Staphylococcus sciuri

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dc.contributor.authorHarrison, Ewan M
dc.contributor.authorPaterson, Gavin K
dc.contributor.authorHolden, Matthew T G
dc.contributor.authorBa, Xiaoliang
dc.contributor.authorRolo, Joana
dc.contributor.authorMorgan, Fiona J E
dc.contributor.authorPichon, Bruno
dc.contributor.authorKearns, Angela
dc.contributor.authorZadoks, Ruth N
dc.contributor.authorPeacock, Sharon J
dc.contributor.authorParkhill, Julian
dc.contributor.authorHolmes, Mark A
dc.date.accessioned2014-12-22T13:01:01Z
dc.date.available2014-12-22T13:01:01Z
dc.date.issued2014-04
dc.identifier.citationHarrison , E M , Paterson , G K , Holden , M T G , Ba , X , Rolo , J , Morgan , F J E , Pichon , B , Kearns , A , Zadoks , R N , Peacock , S J , Parkhill , J & Holmes , M A 2014 , ' A novel hybrid SCC mec - mecC region in Staphylococcus sciuri ' , Journal of Antimicrobial Chemotherapy , vol. 69 , no. 4 , pp. 911-918 . https://doi.org/10.1093/jac/dkt452en
dc.identifier.issn0305-7453
dc.identifier.otherPURE: 104080718
dc.identifier.otherPURE UUID: c6ed3926-82b7-42ef-88c5-b09de6419f73
dc.identifier.otherPubMed: 24302651
dc.identifier.otherScopus: 84896476388
dc.identifier.otherORCID: /0000-0002-4958-2166/work/60196456
dc.identifier.urihttps://hdl.handle.net/10023/5949
dc.description.abstractMethicillin resistance in Staphylococcus spp. results from the expression of an alternative penicillin-binding protein 2a (encoded by mecA) with a low affinity for β-lactam antibiotics. Recently, a novel variant of mecA known as mecC (formerly mecALGA251) was identified in Staphylococcus aureus isolates from both humans and animals. In this study, we identified two Staphylococcus sciuri subsp. carnaticus isolates from bovine infections that harbour three different mecA homologues: mecA, mecA1 and mecC.
dc.language.isoeng
dc.relation.ispartofJournal of Antimicrobial Chemotherapyen
dc.rightsCopyright (c) The Authors 2013. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.subjectβ-lactamsen
dc.subjectMRSAen
dc.subjectmecAen
dc.subjectQH426 Geneticsen
dc.subject.lccQH426en
dc.titleA novel hybrid SCCmec-mecC region in Staphylococcus sciurien
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.contributor.institutionUniversity of St Andrews. Infection Groupen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doihttps://doi.org/10.1093/jac/dkt452
dc.description.statusPeer revieweden


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