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  • Moxifloxacin replacement in contemporary tuberculosis drug regimens is ineffective against persistent Mycobacterium tuberculosis : in the Cornell mouse model 

    Liu, Yingjun; Pertinez, Henry; Davies, Geraint R; Gillespie, Stephen H; Coates, Anthony R; Hu, Yanmin (2018-07) - Journal article
    Tuberculosis (TB), which is caused by Mycobacterium tuberculosis, remains a leading killer worldwide, and disease control is hampered by the ineffective control of persistent infections. Substitution of moxifloxacin for ...
  • Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets 

    Wedge, David C.; Gundem, Gunes; Mitchell, Thomas; Woodstock, Dan J.; Martincorena, Inigo; Ghori, Mohammed; Zamora, Jorge; Butler, Adam; Whitaker, Hayley; Kote-Jarai, Zsofia; Alexandrov, Lumil B.; Van Loo, Peter; Massie, Charlie E.; Dentro, Stefan; Warren, Anne Y.; Verrill, Clare; Berney, Dan M.; Dennis, Nening; Merson, Sue; Hawkins, Steve; Howat, William; Lu, Yong-Jie; Lambert, Adam; Kay, Jonathan; Kremeyer, Barbara; Karaszi, Katalin; Camacho, Niedzica; Luxton, Hayley; Marsden, Luke; Edwards, Sandra; Matthews, Lucy; Bo, Valeria; Leongamornlert, Daniel; McLaren, Stuart; Ng, Anthony; Yu, Yongwei; Zhang, Hongwei; Dadaev, Tokhir; Thomas, Sarah; Easton, Douglas F.; Ahmed, Mahbubl; Bancroft, Elizabeth; Fisher, Cyril; Livni, Naomi; Nicol, David; Tavaré, Simon; Gill, Pelvender; Greenman, Christopher; Khoo, Vincent; Van As, Nicholas; Kumar, Pardeep; Ogden, Christopher; Cahill, Declan; Thompson, Alan; Mayer, Erik; Rowe, Edward; Dudderidge, Tim; Gnanapragasam, Vincent; Shah, Nimish C.; Raine, Keiran; Jones, David; Menzies, Andrew; Stebbings, Lucy; Teague, Jon; Hazell, Steven; Corbishley, Cathy; CamCaP Study Group; de Bono, Johann; Attard, Gerhardt; Isaacs, William; Visakorpi, Tapio; Fraser, Michael; Boutros, Paul C.; Bristow, Robert G.; Workman, Paul; Sander, Chris; The TCGA Consortium; Hamdy, Freddie C.; Futreal, Andrew; McDermott, Ultan; Al-Lazikani, Bissan; Lynch, Andy; Bova, G. Steven; Foster, Christopher S.; Brewer, Daniel S.; Neal, David E.; Cooper, Colin S.; Eeles, Rosalind A. (2018-04-16) - Journal article
    Prostate cancer represents a substantial clinical challenge because it is difficult to predict outcome and advanced disease is often fatal. We sequenced the whole genomes of 112 primary and metastatic prostate cancer ...
  • Scotland and the politics of intelligence accountability 

    Atkinson, Colin; Brooke, Nicholas Steven Thomas; Harris, Brian Andrew (Open Book Publishers, 2017-03) - Book item
    In a democratic society, accountability is the requirement for those in positions of power to provide answers to those whom they serve. Accountability depends, therefore, upon either the presence of an informed, inquisitive, ...
  • Using Genuine Savings for climate policy evaluation with an integrated assessment model 

    Tokimatsu, Koji; Dupuy, Louis; Hanley, Nick (2018-10-12) - Journal article
    There has been a recent increase in efforts to develop broader models to assess the impact of climate change and climate change policies, both in terms of impact measures (beyond GDP) and in terms of modelling complexity ...
  • Parents and peers : parental neighbourhood- and school-level variation in individual neighbourhood outcomes later in life 

    Vuijst, Elise de; van Ham, Maarten (2018-10-11) - Journal article
    Growing up in a disadvantaged parental neighbourhood is related to long-term exposure to similar neighbourhoods as adults. However, there are multiple socio-spatial contexts besides the residential neighbourhood to which ...

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