Now showing items 1-3 of 3

  • Capturing the cloud of diversity reveals complexity and heterogeneity of MRSA carriage, infection and transmission 

    Paterson, Gavin K; Harrison, Ewan M; Murray, Gemma G R; Welch, John J; Warland, James H; Holden, Matthew T G; Morgan, Fiona J E; Ba, Xiaoliang; Koop, Gerrit; Harris, Simon R; Maskell, Duncan J; Peacock, Sharon J; Herrtage, Michael E; Parkhill, Julian; Holmes, Mark A (2015-03-27) - Journal article
    Genome sequencing is revolutionizing clinical microbiology and our understanding of infectious diseases. Previous studies have largely relied on the sequencing of a single isolate from each individual. However, it is not ...
  • A novel hybrid SCCmec-mecC region in Staphylococcus sciuri 

    Harrison, Ewan M; Paterson, Gavin K; Holden, Matthew T G; Ba, Xiaoliang; Rolo, Joana; Morgan, Fiona J E; Pichon, Bruno; Kearns, Angela; Zadoks, Ruth N; Peacock, Sharon J; Parkhill, Julian; Holmes, Mark A (2014-04) - Journal article
    Methicillin resistance in Staphylococcus spp. results from the expression of an alternative penicillin-binding protein 2a (encoded by mecA) with a low affinity for β-lactam antibiotics. Recently, a novel variant of mecA ...
  • A shared population of epidemic methicillin-resistant Staphylococcus aureus 15 circulates in humans and companion animals 

    Harrison, Ewan M; Weinert, Lucy A; Holden, Matthew T G; Welch, John J; Wilson, Katherine; Morgan, Fiona J E; Harris, Simon R; Loeffler, Anette; Boag, Amanda K; Peacock, Sharon J; Paterson, Gavin K; Waller, Andrew S; Parkhill, Julian; Holmes, Mark A (2014-05-13) - Journal article
    Methicillin-resistant Staphylococcus aureus (MRSA) is a global human health problem causing infections in both hospitals and the community. Companion animals, such as cats, dogs, and horses, are also frequently colonized ...