Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast
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Glutathione S-transferase Pi (GST P) has been reported to be a marker of dysplastic lesions. For this reason expression of GST P by intraduct breast carcinoma was evaluated by immunohistochemistry. Thirty-seven of 92 carcinomas (40%) were GST P positive. GST P staining did not correlate with histological variables, c-erbB-2 overexpression or with clinical outcome. The GST P status of recurrences did not correlate with that of the index lesion. There is little evidence that GST P is a useful marker of the potential of intraduct breast carcinoma to become invasive.
Bellamy , C O & Harrison , D J 1994 , ' Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast ' British Journal of Cancer , vol. 69 , no. 1 , pp. 183-185 .
British Journal of Cancer
Copyright Macmillan Press Ltd., 1994. Full text is available as a scanned copy of the original print version from Europe PubMed Central PMC1968756
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