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Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast

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dc.contributor.authorBellamy, C O
dc.contributor.authorHarrison, D J
dc.date.accessioned2015-03-16T13:01:01Z
dc.date.available2015-03-16T13:01:01Z
dc.date.issued1994-01
dc.identifier173625326
dc.identifier33292b59-1521-41e8-bb63-fb4255764c77
dc.identifier0028039807
dc.identifier.citationBellamy , C O & Harrison , D J 1994 , ' Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast ' , British Journal of Cancer , vol. 69 , no. 1 , pp. 183-185 .en
dc.identifier.issn0007-0920
dc.identifier.otherRIS: urn:558959E4E274009601EEF1B0B28E33FE
dc.identifier.otherORCID: /0000-0001-9041-9988/work/64034261
dc.identifier.urihttps://hdl.handle.net/10023/6247
dc.description.abstractGlutathione S-transferase Pi (GST P) has been reported to be a marker of dysplastic lesions. For this reason expression of GST P by intraduct breast carcinoma was evaluated by immunohistochemistry. Thirty-seven of 92 carcinomas (40%) were GST P positive. GST P staining did not correlate with histological variables, c-erbB-2 overexpression or with clinical outcome. The GST P status of recurrences did not correlate with that of the index lesion. There is little evidence that GST P is a useful marker of the potential of intraduct breast carcinoma to become invasive.
dc.format.extent3
dc.format.extent1212992
dc.language.isoeng
dc.relation.ispartofBritish Journal of Canceren
dc.rightsCopyright Macmillan Press Ltd., 1994. Full text is available as a scanned copy of the original print version from Europe PubMed Central PMC1968756en
dc.subjectAdulten
dc.subjectAgeden
dc.subjectBreast neoplasmsen
dc.subjectCarcinoma in situen
dc.subjectCarcinoma, ductal, breasten
dc.subjectEvaluation studies as topicen
dc.subjectFemaleen
dc.subjectFollow-up studiesen
dc.subjectGene expressionen
dc.subjectGlutathione Transferaseen
dc.subjectHumansen
dc.subjectImmunohistochemistryen
dc.subjectIsoenzymesen
dc.subjectMiddle ageden
dc.subjectProto-oncogene proteinsen
dc.subjectReceptor, epidermal growth factoren
dc.subjectReceptor, erbB-2en
dc.subjectR Medicineen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subject.lccRen
dc.subject.lccRC0254en
dc.titleEvaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breasten
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews.School of Medicineen
dc.description.statusPeer revieweden
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968756/en


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