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Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast

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dc.contributor.authorBellamy, C O
dc.contributor.authorHarrison, D J
dc.date.accessioned2015-03-16T13:01:01Z
dc.date.available2015-03-16T13:01:01Z
dc.date.issued1994-01
dc.identifier173625326
dc.identifier33292b59-1521-41e8-bb63-fb4255764c77
dc.identifier0028039807
dc.identifier.citationBellamy , C O & Harrison , D J 1994 , ' Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast ' , British Journal of Cancer , vol. 69 , no. 1 , pp. 183-185 .en
dc.identifier.issn0007-0920
dc.identifier.otherRIS: urn:558959E4E274009601EEF1B0B28E33FE
dc.identifier.otherORCID: /0000-0001-9041-9988/work/64034261
dc.identifier.urihttps://hdl.handle.net/10023/6247
dc.description.abstractGlutathione S-transferase Pi (GST P) has been reported to be a marker of dysplastic lesions. For this reason expression of GST P by intraduct breast carcinoma was evaluated by immunohistochemistry. Thirty-seven of 92 carcinomas (40%) were GST P positive. GST P staining did not correlate with histological variables, c-erbB-2 overexpression or with clinical outcome. The GST P status of recurrences did not correlate with that of the index lesion. There is little evidence that GST P is a useful marker of the potential of intraduct breast carcinoma to become invasive.
dc.format.extent3
dc.format.extent1212992
dc.language.isoeng
dc.relation.ispartofBritish Journal of Canceren
dc.subjectAdulten
dc.subjectAgeden
dc.subjectBreast neoplasmsen
dc.subjectCarcinoma in situen
dc.subjectCarcinoma, ductal, breasten
dc.subjectEvaluation studies as topicen
dc.subjectFemaleen
dc.subjectFollow-up studiesen
dc.subjectGene expressionen
dc.subjectGlutathione Transferaseen
dc.subjectHumansen
dc.subjectImmunohistochemistryen
dc.subjectIsoenzymesen
dc.subjectMiddle ageden
dc.subjectProto-oncogene proteinsen
dc.subjectReceptor, epidermal growth factoren
dc.subjectReceptor, erbB-2en
dc.subjectR Medicineen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subject.lccRen
dc.subject.lccRC0254en
dc.titleEvaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breasten
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.description.statusPeer revieweden
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968756/en


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