Biomedical Sciences Research Complex (BSRC) Research: Recent submissions
Now showing items 21-25 of 28
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Crystal structure of a DNA containing the planar, phenoxazine-derived bi-functional spectroscopic probe Ç
(2011-05) - Journal articleElectron Paramagnetic Resonance (EPR) spectroscopy and fluorescence spectroscopy are complementary biophysical techniques used to examine the structure and dynamics of macromolecules. We have previously described the ... -
Femtosecond optoinjection of intact tobacco BY-2 cells using a reconfigurable photoporation platform
(2013-11-14) - Journal articleA tightly-focused ultrashort pulsed laser beam incident upon a cell membrane has previously been shown to transiently increase cell membrane permeability while maintaining the viability of the cell, a technique known as ... -
Exploring the ultrashort pulse laser parameter space for membrane permeabilisation in mammalian cells.
(2012) - Journal articleThe use of ultrashort femtosecond pulsed lasers to effect membrane permeabilisation and initiate both optoinjection and transfection of cells has recently seen immense interest. We investigate femtosecond laser-induced ... -
Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds
(2013-12) - Journal articleMucopolysaccharidosis (MPS) I is a lysosomal storage disease caused by a deficiency of α-L-iduronidase (IDUA) (EC 3.2.1.76); enzyme replacement therapy is the conventional treatment for this genetic disease. Arabidopsis ... -
Fluorescence suppression using wavelength modulated Raman spectroscopy in fiber-probe-based tissue analysis
(2012-07-09) - Journal articleIn the field of biomedical optics, Raman spectroscopy is a powerful tool for probing the chemical composition of biological samples. In particular, fiber Raman probes play a crucial role for in vivo and ex vivo tissue ...