Biomedical Sciences Research Complex (BSRC) Research

 

The Biomedical Sciences Research Complex (BSRC) is an interdisciplinary research centre involving the Schools of Biology, Chemistry, Medicine and Physics and Astronomy. Research at the centre focuses on infection and immunity, chemical biology, DNA repair and enzymology, and is underpinned by world-class facilities for structural biology, proteomics and synthetic chemistry.

For more information please visit the Biomedical Sciences Research Complex (BSRC) home page.

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Recent Submissions

  • Human cytomegalovirus major immediate early 1 protein targets host chromosomes by docking to the acidic pocket on the nucleosome surface 

    Mücke, Katrin; Paulus, Christina; Bernhardt, Katharina; Gerrer, Katrin; Schön, Kathrin; Fink, Alina; Sauer, Eva-Maria; Asbach-Nitzsche, Alexandra; Harwardt, Thomas; Kieninger, Bärbel; Kremer, Werner; Kalbitzer, Hans Robert; Nevels, Michael (2014-01-15) - Journal article
    The 72-kDa immediate early 1 (IE1) protein encoded by human cytomegalovirus (hCMV) is a nuclearly localized promiscuous regulator of viral and cellular transcription. IE1 has long been known to associate with host mitotic ...

  • 3-2: Invited paper: Color on Demand - Color-tunable OLEDs for lighting and displays 

    Fröbel, Markus; Schwab, Tobias; Kliem, Mona; Lenk, Simone; Leo, Karl; Reineke, Sebastian; Gather, Malte C. (2017) - Journal article
    A device concept for highly efficient OLEDs is introduced that allows to tune the emission color of the device over a broad range of the CIE color gamut. The approach exploits the different polarities of the positive and ...

  • Carpe lucem: harnessing organic light sources for optogenetics 

    Morton, Andrew; Murawski, Caroline; Gather, Malte Christian (Portland Press Ltd., 2016-12-01) - Journal article
    With the advent of optogenetics, numerous functions in cells have been rendered responsive to the experimental delivery of light. The most common implementation of this technique features neurons genetically modified to ...

  • Foundational and translational research opportunities to improve plant health 

    Michelmore, Richard; Coaker, Gitta; Bart, Rebecca; Beattie, Gwyn; Bent, Andrew; Bruce, Toby; Cameron, Duncan; Dangl, Jeff; Dinesh-Kumar, Savithramma; Edwards, Rob; Eves-van den Akker, Sebastian; Gassmann, Walter; Greenberg, Jean; Hanley-Bowdoin, Linda; Harrison, Richard; He, Ping; Harvey, Jagger; Huffaker, Alisa; Hulbert, Scot; Innes, Roger; Jones, Jonathan; Kaloshian, Isghouhi; Kamoun, Sophien; Katagiri, Fumiaki; Leach, Jan; Ma, Wenbo; McDowell, John; Medford, June; Meyers, Blake; Nelson, Rebecca; Oliver, Richard; Qi, Yiping; Saunders, Diane; Shaw, Michael; Smart, Christine; Subudhi, Prasanta; Torrance, Lesley; Tyler, Brett; Valent, Barbara; Walsh, John (2017-07) - Journal article
    This whitepaper reports the deliberations of a workshop focused on biotic challenges to plant health held in Washington, D.C. in September 2016. Ensuring health of food plants is critical to maintaining the quality and ...

  • Orientation of OLED emitter molecules revealed by XRD 

    Murawski, Caroline; Elschner, Chris; Lenk, Simone; Reineke, Sebastian; Gather, Malte Christian (Optical Society of American (OSA), 2016-11-14) - Conference item
    Thin films of the phosphorescent emitters Ir(ppy)3 and Ir(ppy)2(acac) are investigated by GIXRD and GIWAXS. Both molecules form crystalline grains and exhibit a preferred orientation that is pertained even when doped into a host.

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