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Carpe lucem: harnessing organic light sources for optogenetics

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Morton_et_al_TheBiochemist_2016_CarpeLucem.pdf (681.3Kb)
Date
01/12/2016
Author
Morton, Andrew
Murawski, Caroline
Gather, Malte Christian
Keywords
QC Physics
QH426 Genetics
RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
T Technology
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Abstract
With the advent of optogenetics, numerous functions in cells have been rendered responsive to the experimental delivery of light. The most common implementation of this technique features neurons genetically modified to express light-sensitive ion channel proteins, which open specifically in response to pulses of blue light, triggering electrical impulses in neurons. Optogenetics now has matured to a point where in addition to answering fundamental questions about the function of the brain, scientists begin to consider clinical applications. Further progress in this field however will require new ways of delivering light. One of these involves the use of organic light-emitting diodes (OLEDs), a display technology increasingly common in modern-day smart phones, for the optical stimulation of cells.
Citation
Morton , A , Murawski , C & Gather , M C 2016 , ' Carpe lucem : harnessing organic light sources for optogenetics ' The Biochemist , vol. 38 , no. 6 , pp. 4-7 . < http://www.biochemist.org/bio/03806/0004/038060004.pdf >
Publication
The Biochemist
ISSN
0954-982X
Type
Journal article
Rights
© 2016, the Author(s). This work has been made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at www.biochemist.org /
Collections
  • Biomedical Sciences Research Complex (BSRC) Research
  • Physics & Astronomy Research
  • University of St Andrews Research
URL
http://www.biochemist.org/bio/03806/0004/038060004.pdf
URI
http://hdl.handle.net/10023/12236

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