The Biomedical Sciences Research Complex (BSRC) is an interdisciplinary research centre involving the Schools of Biology, Chemistry, Medicine and Physics and Astronomy. Research at the centre focuses on infection and immunity, chemical biology, DNA repair and enzymology, and is underpinned by world-class facilities for structural biology, proteomics and synthetic chemistry.

For more information please visit the Biomedical Sciences Research Complex (BSRC) home page.

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Recent Submissions

  • Plasmodium falciparum choline kinase inhibition leads to a major decrease in phosphatidylethanolamine causing parasite death 

    Serrán-Aguilera, Lucía; Denton, Helen; Rubio-Ruiz, Belén; López-Gutiérrez, Borja; Entrena, Antonio; Izquierdo, Luis; Smith, Terry K; Conejo-García, Ana; Hurtado-Guerrero, Ramon (2016-09-12) - Journal article
    Malaria is a life-threatening disease caused by different species of the protozoan parasite Plasmodium, with P. falciparum being the deadliest. Increasing parasitic resistance to existing antimalarials makes the necessity ...
  • Stathmin is enriched in the developing corticospinal tract 

    Fuller, Heidi; Slade, Robert; Jovanov-Milošević, Nataša; Babić, Mirjana; Sedmak, Goran; Šimić, Goran; Fuszard, Matthew Alexander; Shirran, Sally Lorna; Botting, Catherine Helen; Gates, Monte (2015) - Journal article
    Understanding the intra- and extracellular proteins involved in the development of the corticospinal tract (CST) may offer insights into how the pathway could be regenerated following traumatic spinal cord injury. Currently, ...
  • Updating neuropathology and neuropharmacology of monoaminergic systems 

    Ramsay, Rona R.; De Deurwaerdère, Philippe; Di Giovanni, Giuseppe (2016-07) - Journal item
  • Enhanced optical manipulation of cells using anti-reflection coated microparticles 

    Craig, Derek; McDonald, Alison; Mazilu, Michael; Rendall, Helen Anne; Gunn-Moore, Frank J; Dholakia, Kishan (2015) - Journal article
    We demonstrate the use of anti-reflection (AR) coated microparticles for the enhanced optical manipulation of cells. Specifically, we incubate both CHO-K1 and HL60 cell lines with AR coated titania microparticles and ...
  • Structure of the bacterial sex F pilus reveals an assembly of a stoichiometric protein-phospholipid complex 

    Costa, Tiago R. D.; langovan, Aravindan I; Ukleja, Marta; Redjez, Adam; Santini, Joanne M.; Smith, Terry K.; Egelman, Edward H.; Waksman, Gabriel (2016-09-08) - Journal article
    Conjugative pili are widespread bacterial appendages that play important roles in horizontal gene transfer, in spread of antibiotic resistance genes, and as sites of phage attachment. Among conjugative pili, the F “sex” ...

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