Biomedical Sciences Research Complex (BSRC): Recent submissions
Now showing items 31-35 of 43
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Exploring the ultrashort pulse laser parameter space for membrane permeabilisation in mammalian cells.
(2012) - Journal articleThe use of ultrashort femtosecond pulsed lasers to effect membrane permeabilisation and initiate both optoinjection and transfection of cells has recently seen immense interest. We investigate femtosecond laser-induced ... -
Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds
(2013-12) - Journal articleMucopolysaccharidosis (MPS) I is a lysosomal storage disease caused by a deficiency of α-L-iduronidase (IDUA) (EC 3.2.1.76); enzyme replacement therapy is the conventional treatment for this genetic disease. Arabidopsis ... -
Distance measurements using pulsed EPR : noncovalently bound nitroxide and trityl spin labels
(University of St Andrews, 2013-06-26) - ThesisThe function of biomacromolecules is controlled by their structure and conformational flexibility. Investigating the structure of biologically important macromolecules can, therefore, yield information that could explain ... -
Fluorescence suppression using wavelength modulated Raman spectroscopy in fiber-probe-based tissue analysis
(2012-07-09) - Journal articleIn the field of biomedical optics, Raman spectroscopy is a powerful tool for probing the chemical composition of biological samples. In particular, fiber Raman probes play a crucial role for in vivo and ex vivo tissue ... -
Attenuation of bunyavirus replication by modification of genomic untranslated regions
(University of St Andrews, 2012-11-30) - ThesisBunyamwera orthobunyavirus (BUNV) is the prototype for the family Bunyaviridae. BUNV has a tripartite RNA genome of negative polarity composed of the large(L),medium (M)and small(S)segments. Each segment contains an open ...