Biomedical Sciences Research Complex (BSRC): Recent submissions
Now showing items 36-40 of 43
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Replication of Bunyamwera virus in mosquito cells
(University of St Andrews, 2011) - ThesisThe Bunyaviridae family is one of the largest among RNA viruses, comprising more than 350 serologically distinct viruses. The family is classified into five genera, Orthobunyavirus, Hantavirus, Nairovirus, Phlebovirus, ... -
The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism
(2010-04) - Journal articleBunyamwera virus NSs protein is involved in the inhibition of cellular transcription and the interferon (IFN) response, and it interacts with the Med8 component of Mediator. A spontaneous mutant of a recombinant NSs-deleted ... -
The archaeo-eukaryotic GINS proteins and the archaeal primase catalytic subunit PriS share a common domain
(2010-04-12) - Journal articlePrimase and GINS are essential factors for chromosomal DNA replication in eukaryotic and archaeal cells. Here we describe a previously undetected relationship between the C-terminal domain of the catalytic subunit (PriS) ... -
Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes.
(Spandidos, 2005) - Journal articlePhosphoinositol (PhoIns)-specific phospholipase C enzymes (PLCs) are central to the inositol lipid signaling pathways and contribute to intracellular Ca2+ release and protein kinase C activation. Five distinct classes of ... -
Effects of cationic antimicrobial peptides on Candida and Saccharomyces species
(University of St Andrews, 2010-06-23) - ThesisAntimicrobial peptides (AMPs) are found throughout the animal kingdom and act as a natural defence against a broad spectrum of pathogens. These peptides are toxic to invading organisms without acting on host cells, so are ...