St Andrews Research Repository

Showing items related by title, author, creator and subject.

• Novel cambinol analogues as potential anticancer agents : an improved understanding of sirtuin isoform selectivity 

  Medda, Federico (University of St Andrews, 2011-06-22) - Thesis

  SIRT1 and SIRT2 are two NAD⁺-dependent deacetylases which negatively modulate the activity of p53, a protein which is involved in cell cycle arrest, senescence and apoptosis following genotoxic stress. Part I of the thesis ...

• Crystal structures of two C,N-disubstituted acetamides: 2-(4-chlorophenyl)-N-(2-iodophenyl)acetamide and 2-(4-chlorophenyl)-N-(pyrazin-2-yl)acetamide 

  Narayana, Badiadka; Yathirajan, Hemmige S.; Rathore, Ravindranath; Glidewell, Christopher (2016-09-01) - Journal article

  In the crystal of 2-(4-chloro­phen­yl)-N-(2-iodo­phen­yl)acetamide, C14H11ClINO, molecules are linked by a combination of N—H⋯O and C—H⋯O hydrogen bonds to form a C(4)C(4)[R21(7)] chain of rings and chains of this type are ...

• The crystal structures of two chalcones: (2E)-1-(5-chlorothiophen-2-yl)-3-(2-methylphenyl)prop-2-en-1-one and (2E)-1-(anthracen-9-yl)-3-[4-(propan-2-yl)phenyl]prop-2-en-1-one 

  Girisha, Marisiddaiah; Yathirajan, Hemmige S.; Jasinski, Jerry P.; Glidewell, Christopher (2016-08-01) - Journal article

  In the crystal of compound (I), C14H11ClOS, molecules are linked by C---H···O hydrogen bonds to form simple it C(5) chains. Compound (II), C26H22O, crystallizes with it Z' = 2 in space group it P-1; one of the molecules ...