St Andrews Research Repository

Showing items related by title, author, creator and subject.

• Novel cambinol analogues as potential anticancer agents : an improved understanding of sirtuin isoform selectivity 

  Medda, Federico (University of St Andrews, 2011-06-22) - Thesis

  SIRT1 and SIRT2 are two NAD⁺-dependent deacetylases which negatively modulate the activity of p53, a protein which is involved in cell cycle arrest, senescence and apoptosis following genotoxic stress. Part I of the thesis ...

• The crystal structures of three clozapinium salts : different molecular configurations, and supramolecular assembly in one, two and three dimensions 

  Kaur, M.; Jasinski, J.P.; Yathirajan, H.S.; Kavitha, C.N.; Glidewell, C.; Harrison, W.T.A. (2015-04) - Journal article

  The structures of three salts derived from clozapine, 8-chloro-11-(4-methyl­piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, are reported, namely, clo­za­pin­ium 3,5-di­nitro­benzoate dimethyl sulfoxide monosolvate, ...

• Crystal structures of two C,N-disubstituted acetamides: 2-(4-chlorophenyl)-N-(2-iodophenyl)acetamide and 2-(4-chlorophenyl)-N-(pyrazin-2-yl)acetamide 

  Narayana, Badiadka; Yathirajan, Hemmige S.; Rathore, Ravindranath; Glidewell, Christopher (2016-09-01) - Journal article

  In the crystal of 2-(4-chloro­phen­yl)-N-(2-iodo­phen­yl)acetamide, C14H11ClINO, molecules are linked by a combination of N—H⋯O and C—H⋯O hydrogen bonds to form a C(4)C(4)[R21(7)] chain of rings and chains of this type are ...