Bacteria SAVED from viruses
MetadataShow full item record
Altmetrics Handle Statistics
Altmetrics DOI Statistics
Increasingly, cyclic nucleotide second messengers are implicated in antiviral defense systems in bacteria and archaea as well as in eukaryotes. In this issue of Cell, Lowey et al. describe SAVED—a widespread, uncharacterized cyclic nucleotide sensor protein domain that activates cell defense systems. The structure of SAVED reveals links to the CRISPR system, which also generates cyclic nucleotides in response to viral infection.
White , M F 2020 , ' Bacteria SAVED from viruses ' , Cell , vol. 182 , no. 1 , pp. 5-6 . https://doi.org/10.1016/j.cell.2020.06.015
Copyright © 2020 Elsevier Inc. This work has been made available online in accordance with publisher policies or with permission. Permission for further reuse of this content should be sought from the publisher or the rights holder. This is the author created accepted manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://doi.org/10.1016/j.cell.2020.06.015
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.