Bacteria SAVED from viruses
Abstract
Increasingly, cyclic nucleotide second messengers are implicated in antiviral defense systems in bacteria and archaea as well as in eukaryotes. In this issue of Cell, Lowey et al. describe SAVED—a widespread, uncharacterized cyclic nucleotide sensor protein domain that activates cell defense systems. The structure of SAVED reveals links to the CRISPR system, which also generates cyclic nucleotides in response to viral infection.
Citation
White , M F 2020 , ' Bacteria SAVED from viruses ' , Cell , vol. 182 , no. 1 , pp. 5-6 . https://doi.org/10.1016/j.cell.2020.06.015
Publication
Cell
Status
Peer reviewed
ISSN
0092-8674Type
Journal article
Collections
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