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dc.contributor.authorWhite, Malcolm F.
dc.date.accessioned2021-07-08T23:37:56Z
dc.date.available2021-07-08T23:37:56Z
dc.date.issued2020-07-09
dc.identifier.citationWhite , M F 2020 , ' Bacteria SAVED from viruses ' , Cell , vol. 182 , no. 1 , pp. 5-6 . https://doi.org/10.1016/j.cell.2020.06.015en
dc.identifier.issn0092-8674
dc.identifier.otherPURE: 269159300
dc.identifier.otherPURE UUID: 94ee1d19-fd2f-478f-8c97-01de84de1745
dc.identifier.otherScopus: 85087423197
dc.identifier.otherORCID: /0000-0003-1543-9342/work/77524480
dc.identifier.otherWOS: 000549184500022
dc.identifier.urihttps://hdl.handle.net/10023/23502
dc.description.abstractIncreasingly, cyclic nucleotide second messengers are implicated in antiviral defense systems in bacteria and archaea as well as in eukaryotes. In this issue of Cell, Lowey et al. describe SAVED—a widespread, uncharacterized cyclic nucleotide sensor protein domain that activates cell defense systems. The structure of SAVED reveals links to the CRISPR system, which also generates cyclic nucleotides in response to viral infection.
dc.format.extent2
dc.language.isoeng
dc.relation.ispartofCellen
dc.rightsCopyright © 2020 Elsevier Inc. This work has been made available online in accordance with publisher policies or with permission. Permission for further reuse of this content should be sought from the publisher or the rights holder. This is the author created accepted manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://doi.org/10.1016/j.cell.2020.06.015en
dc.subjectQH301 Biologyen
dc.subjectQR355 Virologyen
dc.subjectBiochemistry, Genetics and Molecular Biology(all)en
dc.subjectT-NDASen
dc.subject.lccQH301en
dc.subject.lccQR355en
dc.titleBacteria SAVED from virusesen
dc.typeJournal articleen
dc.description.versionPostprinten
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doihttps://doi.org/10.1016/j.cell.2020.06.015
dc.description.statusPeer revieweden
dc.date.embargoedUntil2021-07-09
dc.identifier.urlhttps://www.cell.com/cell/fulltext/S0092-8674(20)30746-7en


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