Perceptions of research bronchoscopy in Malawian adults with pulmonary tuberculosis : a cross-sectional study
MetadataShow full item record
Altmetrics Handle Statistics
Altmetrics DOI Statistics
Bronchoscopy is an established research tool in Malawi, enabling collection of pulmonary samples for immunological, pharmacological, and microbiological studies. It is, however, an invasive clinical procedure that offers no direct benefit to volunteering participants when used in a research capacity alone, and thus informed consent is essential. This study aimed to explore TB patients' understanding of research bronchoscopy, what would motivate them to participate in research bronchoscopy, and their concerns, in order to inform consenting processes for future clinical studies. We used a qualitative research design. Two focus group discussions were conducted with community members and TB patients to understand their perceptions of bronchoscopy. Transcripts were coded by multiple coauthors and thematic content analysis was used to analyse main findings. We found that Malawian patients with pulmonary TB were willing to participate in a study using research bronchoscopy for health assessment and access to improved healthcare. We identified information of value to potential participants when consenting to that may lessen some of the anxieties expressed by participants. Patient and public involvement is essential to improve informed consent and institutional trust.
McCallum , A D , Nyirenda , D , Lora , W , Khoo , S H , Sloan , D J , Mwandumba , H C , Desmond , N & Davies , G R 2016 , ' Perceptions of research bronchoscopy in Malawian adults with pulmonary tuberculosis : a cross-sectional study ' , PLoS ONE , vol. 11 , no. 10 , e0165734 , pp. 1-12 . https://doi.org/10.1371/journal.pone.0165734
Copyright :© 2016 McCallum et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
DescriptionFunding: Liverpool Integrated Clinical Academic Training Programme, experience at another institution (ADM); Wellcome Trust Clinical PhD Fellowship 105392/B/14/Z.
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.