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3T MRI investigation of cardiac left ventricular structure and function in a UK population : he Tayside screening for the prevention of cardiac events (TASCFORCE) study
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dc.contributor.author | Gandy, Stephen J. | |
dc.contributor.author | Lambert, Matthew | |
dc.contributor.author | Belch, Jill | |
dc.contributor.author | Cavin, Ian | |
dc.contributor.author | Crowe, Elena | |
dc.contributor.author | Littleford, Roberta | |
dc.contributor.author | MacFarlane, Jennifer A | |
dc.contributor.author | Matthew, Shona Z | |
dc.contributor.author | Martin, Patricia | |
dc.contributor.author | Nicholas, R. Stephen | |
dc.contributor.author | Struthers, Allan | |
dc.contributor.author | Sullivan, Frank | |
dc.contributor.author | Waugh, Shelley A. | |
dc.contributor.author | White, Richard D. | |
dc.contributor.author | Weir-McCall, Jonathan R. | |
dc.contributor.author | Houston, J. Graeme | |
dc.date.accessioned | 2017-05-12T08:30:11Z | |
dc.date.available | 2017-05-12T08:30:11Z | |
dc.date.issued | 2016-11 | |
dc.identifier | 249969086 | |
dc.identifier | 903bc3eb-a8fd-4578-96b3-7ef8791775d0 | |
dc.identifier | 27143317 | |
dc.identifier | 84964951696 | |
dc.identifier.citation | Gandy , S J , Lambert , M , Belch , J , Cavin , I , Crowe , E , Littleford , R , MacFarlane , J A , Matthew , S Z , Martin , P , Nicholas , R S , Struthers , A , Sullivan , F , Waugh , S A , White , R D , Weir-McCall , J R & Houston , J G 2016 , ' 3T MRI investigation of cardiac left ventricular structure and function in a UK population : he Tayside screening for the prevention of cardiac events (TASCFORCE) study ' , Journal of Magnetic Resonance Imaging , vol. 44 , no. 5 , pp. 1186-1196 . https://doi.org/10.1002/jmri.25267 | en |
dc.identifier.issn | 1053-1807 | |
dc.identifier.other | PubMedCentral: PMC5082537 | |
dc.identifier.other | ORCID: /0000-0002-6623-4964/work/33508483 | |
dc.identifier.uri | https://hdl.handle.net/10023/10759 | |
dc.description | Contract grant sponsor: Souter Charitable Trust, and Chest, Heart and Stroke Scotland; Contract grant sponsor: Wellcome Trust; contract grant number: WT 085664 (Clinical Research Fellowship to J.W-McC.) | en |
dc.description.abstract | Purpose: To scan a volunteer population using 3.0T magnetic resonance imaging (MRI). MRI of the left ventricular (LV) structure and function in healthy volunteers has been reported extensively at 1.5T. Materials and Methods: A population of 1528 volunteers was scanned. A standardized approach was taken to acquire steady-state free precession (SSFP) LV data in the short-axis plane, and images were quantified using commercial software. Six observers undertook the segmentation analysis. Results: Mean values (±standard deviation, SD) were: ejection fraction (EF) = 69 ± 6%, end diastolic volume index (EDVI) = 71 ± 13 ml/m2 , end systolic volume index (ESVI) = 22 ± 7 ml/m2 , stroke volume index (SVI) = 49 ± 8 ml/m2 , and LV mass index (LVMI) = 55 ± 12 g/m2 . The mean EF was slightly larger for females (69%) than for males (68%), but all other variables were smaller for females (EDVI 68v77 ml/m2 , ESVI 21v25 ml/m2 , SVI 46v52 ml/m2 , LVMI 49v64 g/m2, all P < 0.05). The mean LV volume data mostly decreased with each age decade (EDVI males: -2.9 ± 1.3 ml/m2 , females: -3.1 ± 0.8 ml/m2 ; ESVI males: -1.3 ± 0.7 ml/m2 , females: -1.7 ± 0.5 ml/m2 ; SVI males: -1.7 ± 0.9 ml/m2 , females: -1.4 ± 0.6 ml/m2 ; LVMI males: -1.6 ± 1.1 g/m2 , females: -0.2 ± 0.6 g/m2 but the mean EF was virtually stable in males (0.6 ± 0.6%) and rose slightly in females (1.2 ± 0.5%) with age. Conclusion: LV reference ranges are provided in this population-based MR study at 3.0T. The variables are similar to those described at 1.5T, including variations with age and gender. These data may help to support future population-based MR research studies that involve the use of 3.0T MRI scanners. | |
dc.format.extent | 11 | |
dc.format.extent | 199684 | |
dc.language.iso | eng | |
dc.relation.ispartof | Journal of Magnetic Resonance Imaging | en |
dc.subject | Cardiac | en |
dc.subject | MRI | en |
dc.subject | 3.0T | en |
dc.subject | Left ventricle | en |
dc.subject | Population | en |
dc.subject | RA0421 Public health. Hygiene. Preventive Medicine | en |
dc.subject | RC Internal medicine | en |
dc.subject | NDAS | en |
dc.subject | SDG 3 - Good Health and Well-being | en |
dc.subject.lcc | RA0421 | en |
dc.subject.lcc | RC | en |
dc.title | 3T MRI investigation of cardiac left ventricular structure and function in a UK population : he Tayside screening for the prevention of cardiac events (TASCFORCE) study | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. School of Medicine | en |
dc.identifier.doi | https://doi.org/10.1002/jmri.25267 | |
dc.description.status | Peer reviewed | en |
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