α-Methylenation of methyl propanoate via catalytic dehydrogenation of methanol
Abstract
A one-pot system for the conversion of methyl propanoate (MeP) to methyl methacrylate (MMA) has been investigated. In particular, this study is focused on the possibility of performing catalytic dehydrogenation of methanol for the in situ production of anhydrous formaldehyde, which is then consumed in a one-pot base-catalysed condensation with MeP to afford methyl 3-hydroxy-2-methylpropanoate, which spontaneously dehydrogenates to MMA, some of which is subsequently hydrogenated to methyl 2-methypropanoate (MiBu).
Citation
Lorusso , P , Coetzee , J , Eastham , G & Cole-Hamilton , D J 2016 , ' α-Methylenation of methyl propanoate via catalytic dehydrogenation of methanol ' , ChemCatChem , vol. 8 , no. 1 , pp. 222–227 . https://doi.org/10.1002/cctc.201500763
Publication
ChemCatChem
Status
Peer reviewed
ISSN
1867-3880Type
Journal article
Collections
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.