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A one-pot synthesis of symmetrical and unsymmetrical dipeptide ureas

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dc.contributor.authorAbou Fayad, Antoine
dc.contributor.authorPubill Ulldemolins, Cristina
dc.contributor.authorSharma, Sunil Vishnuprasadji
dc.contributor.authorDay, David
dc.contributor.authorGoss, Rebecca Jane Miriam
dc.date.accessioned2016-07-29T23:30:59Z
dc.date.available2016-07-29T23:30:59Z
dc.date.issued2015-09
dc.identifier197715351
dc.identifier8dfd4a46-1a2e-4a03-8aba-4d8807a1475b
dc.identifier84939639786
dc.identifier000360064500014
dc.identifier.citationAbou Fayad , A , Pubill Ulldemolins , C , Sharma , S V , Day , D & Goss , R J M 2015 , ' A one-pot synthesis of symmetrical and unsymmetrical dipeptide ureas ' , European Journal of Organic Chemistry , vol. 25 , pp. 5603-5609 . https://doi.org/10.1002/ejoc.201500589en
dc.identifier.issn1434-193X
dc.identifier.urihttps://hdl.handle.net/10023/9228
dc.descriptionWe gratefully acknowledge financial support from the BBSRC (Grant no. BB/I022910/1 and the European Commission (Seventh Framework Programme, Collaborative project "BlueGenics", Grant no. 311848).en
dc.description.abstractWe describe a flexible and high yielding synthesis of 1,3-disubstituted ureas, that allows for the construction of both symmetrical and unsymmetrical dipeptide ureas, including easy access to 13C labelled ureas, from amino acids and carbon dioxide at atmospheric pressure.
dc.format.extent8
dc.format.extent7037853
dc.format.extent735070
dc.language.isoeng
dc.relation.ispartofEuropean Journal of Organic Chemistryen
dc.subjectPeptidesen
dc.subjectDipeptideen
dc.subjectUreaen
dc.subjectIsotopic labellingen
dc.subjectQD Chemistryen
dc.subjectNDASen
dc.subject.lccQDen
dc.titleA one-pot synthesis of symmetrical and unsymmetrical dipeptide ureasen
dc.typeJournal articleen
dc.contributor.sponsorBBSRCen
dc.contributor.institutionUniversity of St Andrews. School of Chemistryen
dc.contributor.institutionUniversity of St Andrews. EaSTCHEMen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doi10.1002/ejoc.201500589
dc.description.statusPeer revieweden
dc.date.embargoedUntil2016-07-30
dc.identifier.grantnumberBB/I022910/2en


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