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New insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modelling

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dc.contributor.authorCampbell, C. Louise
dc.contributor.authorWood, Kenneth
dc.contributor.authorBrown, C. Tom A
dc.contributor.authorMoseley, Harry
dc.contributor.editorChoi, Bernard
dc.contributor.editorKollias, Nikiforos
dc.contributor.editorZeng, Haishan
dc.contributor.editorWook Kang, Hyun
dc.contributor.editorWong, Brian J F
dc.contributor.editorIlgner, Justus F
dc.contributor.editorTearney, Guillermo J
dc.contributor.editorGregory, Kenton W
dc.contributor.editorMarcu, Laura
dc.contributor.editorSkala, Melissa C
dc.contributor.editorCampagnola, Paul J
dc.contributor.editorMandelis, Andreas
dc.contributor.editorMorris, Michael D
dc.date.accessioned2016-06-21T15:30:03Z
dc.date.available2016-06-21T15:30:03Z
dc.date.issued2016-02-29
dc.identifier.citationCampbell , C L , Wood , K , Brown , C T A & Moseley , H 2016 , New insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modelling . in B Choi , N Kollias , H Zeng , H Wook Kang , B J F Wong , J F Ilgner , G J Tearney , K W Gregory , L Marcu , M C Skala , P J Campagnola , A Mandelis & M D Morris (eds) , Photonic Therapeutics and Diagnostics XII . , 96890Q , Proceedings of SPIE , vol. 9689 , SPIE , Photonic Therapeutics and Diagnostics XII , San Francisco , United States , 13/02/16 . https://doi.org/10.1117/12.2212240en
dc.identifier.citationconferenceen
dc.identifier.isbn9781628419245
dc.identifier.issn0277-786X
dc.identifier.otherPURE: 243564707
dc.identifier.otherPURE UUID: 0c47628b-4604-4d40-86ab-d42626c8d784
dc.identifier.otherScopus: 84973369413
dc.identifier.otherWOS: 000377396200022
dc.identifier.otherORCID: /0000-0002-4405-6677/work/86537153
dc.identifier.urihttps://hdl.handle.net/10023/9027
dc.descriptionWe acknowledge the support of the UK Engineering and Physics Sciences Research Council (EPSRC) for funding through a studentship for C L Campbell (EP/K503162/1), the Alfred Stewart Trust as well as the BMLA Education Award.en
dc.description.abstractPhotodynamic therapy (PDT) has been theoretically investigated using a Monte Carlo radiation transfer (MCRT) model. By including complex three dimensional (3D) tumour models a more appropriate representation of the treatment was achieved. The 3D clustered tumour model was compared to a smooth model, resulting in a significantly deeper penetration associated with the clustered model. The results from the work presented here indicates that light might penetrate deeper than suggested by 2D or simple layered models.
dc.language.isoeng
dc.publisherSPIE
dc.relation.ispartofPhotonic Therapeutics and Diagnostics XIIen
dc.relation.ispartofseriesProceedings of SPIEen
dc.rights© 2016, SPIE. This work is made available online in accordance with the publisher’s policies. This is the final published version of the work, which was originally published at proceedings.spiedigitallibrary.org / https://dx.doi.org/10.1117/12.2212240en
dc.subjectDaylight PDTen
dc.subjectFractal modelen
dc.subjectMonte Carlo radiation transferen
dc.subjectNon-homogeneous tumour modelen
dc.subjectPhotodynamic therapyen
dc.subjectSkin opticsen
dc.subjectAtomic and Molecular Physics, and Opticsen
dc.subjectElectronic, Optical and Magnetic Materialsen
dc.subjectBiomaterialsen
dc.subjectRadiology Nuclear Medicine and imagingen
dc.subjectNDASen
dc.titleNew insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modellingen
dc.typeConference itemen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. School of Physics and Astronomyen
dc.identifier.doihttps://doi.org/10.1117/12.2212240


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