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dc.contributor.authorKelsey, Thomas W
dc.contributor.authorGinbey, Eleanor
dc.contributor.authorChowdhury, Moti M
dc.contributor.authorBath, Louise E
dc.contributor.authorAnderson, Richard A
dc.contributor.authorWallace, W Hamish B
dc.date.accessioned2016-06-14T08:30:08Z
dc.date.available2016-06-14T08:30:08Z
dc.date.issued2016-06-13
dc.identifier243133889
dc.identifier0b2294dd-558f-4be0-b0d4-1d2db0bef2b9
dc.identifier27295032
dc.identifier27295032
dc.identifier84976412281
dc.identifier000377821300038
dc.identifier.citationKelsey , T W , Ginbey , E , Chowdhury , M M , Bath , L E , Anderson , R A & Wallace , W H B 2016 , ' A validated normative model for human uterine volume from birth to age 40 years ' , PLoS One , vol. 11 , no. 6 , e0157375 . https://doi.org/10.1371/journal.pone.0157375 , https://doi.org/10.1371/journal.pone.0157375en
dc.identifier.issn1932-6203
dc.identifier.otherPubMedCentral: PMC4905658
dc.identifier.otherORCID: /0000-0002-8091-1458/work/27201528
dc.identifier.urihttps://hdl.handle.net/10023/8973
dc.description.abstractTransabdominal pelvic ultrasound and/or pelvic Magnetic Resonance Imaging are safe, accurate and non - invasive means of determining the size and configuration of the internal female genitalia. The assessment of uterine size and volume is helpful in the assessment of many conditions including disorders of sex development, precocious or delayed puberty, infertility and menstrual disorders. Using our own data from the assessment of MRI scans in healthy young females and data extracted from four studies that assessed uterine volume using transabdominal ultrasound in healthy females we have derived and validated a normative model of uterine volume from birth to age 40 years. This shows that uterine volume increases across childhood, with a faster increase in adolescence reflecting the influence of puberty, followed by a slow but progressive rise during adult life. The model suggests that around 84% of the variation in uterine volumes in the healthy population up to age 40 is due to age alone . The derivation of a validated normative model for uterine volume from birth to age 40 years has important clinical applications by providing age-related reference values for uterine volume.
dc.format.extent14
dc.format.extent3040670
dc.language.isoeng
dc.relation.ispartofPLoS Oneen
dc.subjectJournal Articleen
dc.subjectRG Gynecology and obstetricsen
dc.subjectQA75 Electronic computers. Computer scienceen
dc.subjectAgricultural and Biological Sciences(all)en
dc.subjectBiochemistry, Genetics and Molecular Biology(all)en
dc.subjectMedicine(all)en
dc.subjectDASen
dc.subject.lccRGen
dc.subject.lccQA75en
dc.titleA validated normative model for human uterine volume from birth to age 40 yearsen
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Computer Scienceen
dc.contributor.institutionUniversity of St Andrews. Centre for Interdisciplinary Research in Computational Algebraen
dc.identifier.doi10.1371/journal.pone.0157375
dc.description.statusPeer revieweden
dc.identifier.urlhttp://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0157375en


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