Efficient synthesis of novel chalcogen-containing derivatives of DNA nucleobases
Date
25/03/2015Author
Grant ID
EP/K503940/1
EP/K031252/1
EP/K039210/1
Keywords
Metadata
Show full item recordAbstract
The formation of a library of chalcogen-containing DNA nucleobase derivatives is presented. Reacting easily accessible 9-(2-bromoethyl)adenine with chalcogen-containing nucleophilic reagents led to a series of novel heteroatom derivatives incorporating S, Se and Te atoms prepared in satisfactory yields. Two representative X-ray structures are reported
Citation
Hua , G , Du , J , Cordes , D B , Slawin , A M Z & Woollins , J D 2015 , ' Efficient synthesis of novel chalcogen-containing derivatives of DNA nucleobases ' , Tetrahedron , vol. 71 , no. 12 , pp. 1792-1798 . https://doi.org/10.1016/j.tet.2015.02.005
Publication
Tetrahedron
Status
Non peer reviewed
ISSN
0040-4020Type
Journal article
Rights
2015 Elsevier Ltd. All rights reserved. This is the author’s version of a work that was accepted for publication in Tetrahedron. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Tetrahedron, 2015, DOI: http://dx.doi.org/10.1016/j.tet.2015.02.005
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