Efficient synthesis of novel chalcogen-containing derivatives of DNA nucleobases
Date
25/03/2015Author
Grant ID
EP/K503940/1
EP/K031252/1
EP/K039210/1
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Show full item recordAbstract
The formation of a library of chalcogen-containing DNA nucleobase derivatives is presented. Reacting easily accessible 9-(2-bromoethyl)adenine with chalcogen-containing nucleophilic reagents led to a series of novel heteroatom derivatives incorporating S, Se and Te atoms prepared in satisfactory yields. Two representative X-ray structures are reported
Citation
Hua , G , Du , J , Cordes , D B , Slawin , A M Z & Woollins , J D 2015 , ' Efficient synthesis of novel chalcogen-containing derivatives of DNA nucleobases ' , Tetrahedron , vol. 71 , no. 12 , pp. 1792-1798 . https://doi.org/10.1016/j.tet.2015.02.005
Publication
Tetrahedron
Status
Non peer reviewed
ISSN
0040-4020Type
Journal article
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