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dc.contributor.authorMutai, John
dc.contributor.authorVinayak, Sudhir
dc.contributor.authorStones, William
dc.contributor.authorHacking, Nigel
dc.contributor.authorMariara, Charles
dc.date.accessioned2015-07-14T11:10:01Z
dc.date.available2015-07-14T11:10:01Z
dc.date.issued2015-03-31
dc.identifier.citationMutai , J , Vinayak , S , Stones , W , Hacking , N & Mariara , C 2015 , ' Uterine Fibroid Embolization for symptomatic fibroids : study at a teaching hospital in Kenya ' , Journal of Clinical Imaging Science , vol. 5 , 18 . https://doi.org/10.4103/2156-7514.154351en
dc.identifier.otherPURE: 181077103
dc.identifier.otherPURE UUID: df104728-671e-43fd-b94b-9ce0ea2d680a
dc.identifier.otherScopus: 84940524927
dc.identifier.urihttp://hdl.handle.net/10023/6979
dc.descriptionThis study was funded by the Aga Khan University Date of Acceptance: 24/02/2015en
dc.description.abstractObjective: Characterization of magnetic (MRI) features in women undergoing uterine fibroid embolization (UFE) and identification of clinical correlates in an African population. Materials and Methods: Patients with symptomatic fibroids who are selected to undergo UFE at the hospital formed the study population. The baseline MRI features, baseline symptom score, short-term imaging outcome, and mid-term symptom scores were analyzed for interval changes. Assessment of potential associations between short-term imaging features and mid-term symptom scores was also done. Results: UFE resulted in statistically significant reduction (P < 0.001) of dominant fibroid, uterine volumes, and reduction of symptom severity scores, which were 43.7%, 40.1%, and 37.8%, respectively. Also, 59% of respondents had more than 10 fibroids. The predominant location of the dominant fibroid was intramural. No statistically significant association was found between clinical and radiological outcome. Conclusion: The response of uterine fibroids to embolization in the African population is not different from the findings reported in other studies from the west. The presence of multiple and large fibroids in this study is consistent with the case mix described in other studies of African-American populations. Patient counseling should emphasize the independence of volume reduction and symptom improvement. Though volume changes are of relevance for the radiologist in understanding the evolution of the condition and identifying potential technical treatment failures, it should not be the main basis of evaluation of treatment success.
dc.format.extent9
dc.language.isoeng
dc.relation.ispartofJournal of Clinical Imaging Scienceen
dc.rightsCopyright: © 2015 Mutai JK. This is an open‑access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en
dc.subjectAfrican womenen
dc.subjectEmbolizationen
dc.subjectFibroiden
dc.subjectResponseen
dc.subjectR Medicineen
dc.subjectNDASen
dc.subject.lccRen
dc.titleUterine Fibroid Embolization for symptomatic fibroids : study at a teaching hospital in Kenyaen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.contributor.institutionUniversity of St Andrews. Global Health Implementation Groupen
dc.identifier.doihttps://doi.org/10.4103/2156-7514.154351
dc.description.statusPeer revieweden
dc.identifier.urlhttp://www.clinicalimagingscience.org/text.asp?2015/5/1/18/154351en


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