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Simultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensors

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dc.contributor.authorJamieson, L.E.
dc.contributor.authorJaworska, A.
dc.contributor.authorJiang, J.
dc.contributor.authorBaranska, M.
dc.contributor.authorHarrison, D.J.
dc.contributor.authorCampbell, C.J.
dc.date.accessioned2015-07-14T10:40:01Z
dc.date.available2015-07-14T10:40:01Z
dc.date.issued2015-04-07
dc.identifier.citationJamieson , L E , Jaworska , A , Jiang , J , Baranska , M , Harrison , D J & Campbell , C J 2015 , ' Simultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensors ' , Analyst , vol. 140 , no. 7 , pp. 2330-2335 . https://doi.org/10.1039/c4an02365jen
dc.identifier.issn0003-2654
dc.identifier.otherPURE: 181298533
dc.identifier.otherPURE UUID: 4b9f7cb3-ae48-484b-af80-3a6abf7aa7fa
dc.identifier.otherScopus: 84925310630
dc.identifier.otherWOS: 000351405900033
dc.identifier.otherPubMed: 25700000
dc.identifier.otherORCID: /0000-0001-9041-9988/work/64034324
dc.identifier.urihttps://hdl.handle.net/10023/6978
dc.descriptionThe authors gratefully acknowledge the School of Chemistry at the University of Edinburgh, a Neil Campbell Travel Award, the Faculty of Chemistry at Jagiellonian University and Jagiellonian Centre for Experimental Therapeutics (JCET). A. J.’s work was supported by National Center of Science (grant PRELUDIUM DEC-2012/05/N/ST4/00218) and by the European Union from the resources of the European Regional Development Fund under the Innovative Economy Programme (grant coordinated by JCET-UJ, No POIG.01.01.02-00-069/09).en
dc.description.abstractIntracellular redox potential is a highly regulated cellular characteristic and is critically involved in maintaining cellular health and function. The dysregulation of redox potential can result in the initiation and progression of numerous diseases. Redox potential is determined by the balance of oxidants and reductants in the cell and also by pH. For this reason a technique for quantitative measurement of intracellular redox potential and pH is highly desirable. In this paper we demonstrate how surface enhanced Raman scattering (SERS) nanosensors can be used for multiplexed measurement of both pH and redox potential in live single cells.
dc.format.extent6
dc.language.isoeng
dc.relation.ispartofAnalysten
dc.rightsThis article is published under a Creative Commons Attribution 3.0 Unported Licence.en
dc.subjectQR Microbiologyen
dc.subjectQD Chemistryen
dc.subjectNDASen
dc.subject.lccQRen
dc.subject.lccQDen
dc.titleSimultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensorsen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.identifier.doihttps://doi.org/10.1039/c4an02365j
dc.description.statusPeer revieweden
dc.identifier.urlhttp://www.rsc.org/suppdata/an/c4/c4an02365j/c4an02365j1.pdfen


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