Show simple item record

Files in this item

Thumbnail
Name:
steinig2015bmcgenomics388.pdf
Size:
1.437Mb
Format:
PDF
View/Open

Single-molecule sequencing reveals the molecular basis of multidrug-resistance in ST772 methicillin-resistant Staphylococcus aureus

Item metadata

dc.contributor.authorSteinig, Eike J
dc.contributor.authorAndersson, Patiyan
dc.contributor.authorHarris, Simon R
dc.contributor.authorSarovich, Derek S
dc.contributor.authorManoharan, Anand
dc.contributor.authorCoupland, Paul
dc.contributor.authorHolden, Matthew Tg
dc.contributor.authorParkhill, Julian
dc.contributor.authorBentley, Stephen D
dc.contributor.authorRobinson, D Ashley
dc.contributor.authorTong, Steven Yc
dc.date.accessioned2015-05-21T09:01:04Z
dc.date.available2015-05-21T09:01:04Z
dc.date.issued2015-05-16
dc.identifier188980413
dc.identifier9a27a458-a5b6-4591-86b6-3ca46365b21d
dc.identifier25981586
dc.identifier84929322411
dc.identifier000354528500001
dc.identifier.citationSteinig , E J , Andersson , P , Harris , S R , Sarovich , D S , Manoharan , A , Coupland , P , Holden , M T , Parkhill , J , Bentley , S D , Robinson , D A & Tong , S Y 2015 , ' Single-molecule sequencing reveals the molecular basis of multidrug-resistance in ST772 methicillin-resistant Staphylococcus aureus ' , BMC Genomics , vol. 16 , 388 . https://doi.org/10.1186/s12864-015-1599-9en
dc.identifier.issn1471-2164
dc.identifier.otherORCID: /0000-0002-4958-2166/work/60196471
dc.identifier.urihttps://hdl.handle.net/10023/6676
dc.descriptionYCT is an Australian National Health and Medical Research Council Career Development Fellow (1065736). DAR was supported in part by National Institutes of Health grant GM080602. SRH, PC, MTGH, JP and SDB were supported by Wellcome Trust grant 098051.en
dc.description.abstractMethicillin-resistant Staphylococcus aureus (MRSA) is a major cause of hospital-associated infection, but there is growing awareness of the emergence of multidrug-resistant lineages in community settings around the world. One such lineage is ST772-MRSA-V, which has disseminated globally and is increasingly prevalent in India. Here, we present the complete genome sequence of DAR4145, a strain of the ST772-MRSA-V lineage from India, and investigate its genomic characteristics in regards to antibiotic resistance and virulence factors.
dc.format.extent10
dc.format.extent1507228
dc.language.isoeng
dc.relation.ispartofBMC Genomicsen
dc.subjectStaphylococcus aureasen
dc.subjectMRSAen
dc.subjectST722en
dc.subjectAntibiotic resistanceen
dc.subjectMobile genetic elementsen
dc.subjectComplete genomeen
dc.subjectDAR4145en
dc.subjectIndiaen
dc.subjectR Medicineen
dc.subjectQH301 Biologyen
dc.subjectDASen
dc.subject.lccRen
dc.subject.lccQH301en
dc.titleSingle-molecule sequencing reveals the molecular basis of multidrug-resistance in ST772 methicillin-resistant Staphylococcus aureusen
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.contributor.institutionUniversity of St Andrews. Infection Groupen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doi10.1186/s12864-015-1599-9
dc.description.statusPeer revieweden


This item appears in the following Collection(s)

Show simple item record

Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.