A cooperative Pd-Cu system for direct C-H bond arylation
Abstract
A novel and efficient method for C-H arylation using well-defined Pd- and Cu-NHC systems has been developed. This process promotes the challenging construction of C-C bonds from arenes or heteroarenes using aryl bromides and chlorides. Mechanistic studies show that [Cu(OH)(NHC)] plays a key role in the C-H activation and is involved in the transmetallation with the Pd-NHC co-catalyst.
Citation
Lesieur , M , Lazreg , F & Cazin , C S J 2014 , ' A cooperative Pd-Cu system for direct C-H bond arylation ' , Chemical Communications , vol. 50 , no. 64 , pp. 8927-8929 . https://doi.org/10.1039/c4cc03201b
Publication
Chemical Communications
Status
Peer reviewed
ISSN
1359-7345Type
Journal article
Rights
Copyright 2014 The Authors. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (http://creativecommons.org/licenses/by/3.0/)
Description
The authors are grateful to the Royal Society (University Research Fellowship to CSJC) for financial support.Collections
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.