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dc.contributor.authorOwen, Christopher B
dc.contributor.authorHughes, David J
dc.contributor.authorBaquero-Perez, Belinda
dc.contributor.authorBerndt, Anja
dc.contributor.authorSchumann, Sophie
dc.contributor.authorJackson, Brian R
dc.contributor.authorWhitehouse, Adrian
dc.date.accessioned2015-01-15T11:31:03Z
dc.date.available2015-01-15T11:31:03Z
dc.date.issued2014-11
dc.identifier158297148
dc.identifier74af9025-132d-469a-898d-1a44529bd8f2
dc.identifier25279171
dc.identifier.citationOwen , C B , Hughes , D J , Baquero-Perez , B , Berndt , A , Schumann , S , Jackson , B R & Whitehouse , A 2014 , ' Utilising proteomic approaches to understand oncogenic human herpesviruses (Review) ' , Molecular and Clinical Oncology , vol. 2 , no. 6 , pp. 891-903 . https://doi.org/10.3892/mco.2014.341en
dc.identifier.issn2049-9450
dc.identifier.otherORCID: /0000-0002-0090-5710/work/39632382
dc.identifier.urihttps://hdl.handle.net/10023/6003
dc.descriptionThis study was supported in part by BBSRC, YCR, Wellcome Trust and AICR.en
dc.description.abstractThe γ-herpesviruses Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus are successful pathogens, each infecting a large proportion of the human population. These viruses persist for the life of the host and may each contribute to a number of malignancies, for which there are currently no cures. Large-scale proteomic-based approaches provide an excellent means of increasing the collective understanding of the proteomes of these complex viruses and elucidating their numerous interactions within the infected host cell. These large-scale studies are important for the identification of the intricacies of viral infection and the development of novel therapeutics against these two important pathogens.
dc.format.extent13
dc.format.extent837218
dc.language.isoeng
dc.relation.ispartofMolecular and Clinical Oncologyen
dc.subjectProteomicsen
dc.subjectMass spectrometryen
dc.subjectGamma-herpesvirusen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectQH301 Biologyen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subject.lccRC0254en
dc.subject.lccQH301en
dc.titleUtilising proteomic approaches to understand oncogenic human herpesviruses (Review)en
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doi10.3892/mco.2014.341
dc.description.statusPeer revieweden


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