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Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy

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dc.contributor.authorDe Smet, Birgit
dc.contributor.authorSarovich, Derek S
dc.contributor.authorPrice, Erin P
dc.contributor.authorMayo, Mark
dc.contributor.authorTheobald, Vanessa
dc.contributor.authorKham, Chun
dc.contributor.authorHeng, Seiha
dc.contributor.authorPhe, Thong
dc.contributor.authorHolden, Matthew T G
dc.contributor.authorParkhill, Julian
dc.contributor.authorPeacock, Sharon J
dc.contributor.authorSpratt, Brian G
dc.contributor.authorJacobs, Jan
dc.contributor.authorVandamme, Peter
dc.contributor.authorCurrie, Bart J
dc.date.accessioned2014-12-19T14:01:02Z
dc.date.available2014-12-19T14:01:02Z
dc.date.issued2015-01
dc.identifier159052645
dc.identifier541769e1-1098-4f51-872a-4dc608024428
dc.identifier25392354
dc.identifier84919475381
dc.identifier000346502200051
dc.identifier.citationDe Smet , B , Sarovich , D S , Price , E P , Mayo , M , Theobald , V , Kham , C , Heng , S , Phe , T , Holden , M T G , Parkhill , J , Peacock , S J , Spratt , B G , Jacobs , J , Vandamme , P & Currie , B J 2015 , ' Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy ' , Journal of Clinical Microbiology , vol. 53 , no. 1 , pp. 323-326 . https://doi.org/10.1128/JCM.02574-14en
dc.identifier.issn0095-1137
dc.identifier.otherORCID: /0000-0002-4958-2166/work/60196372
dc.identifier.urihttps://hdl.handle.net/10023/5943
dc.descriptionWhole-genome sequencing of the four isolates used in this study was supported by Wellcome Trust grant 098051, awarded to the Wellcome Trust Sanger Institute. This work was also supported by project grants from the Australian National Health and Medical Research Council and the Wellcome Trust. S.J.P. receives funding from the NIHR Cambridge Biomedical Research Centre.en
dc.description.abstractBurkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian origin, and confirmed that these shared STs were due to homoplasy.
dc.format.extent474869
dc.language.isoeng
dc.relation.ispartofJournal of Clinical Microbiologyen
dc.subjectQR Microbiologyen
dc.subjectDASen
dc.subject.lccQRen
dc.titleWhole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasyen
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.contributor.institutionUniversity of St Andrews. Infection Groupen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doi10.1128/JCM.02574-14
dc.description.statusPeer revieweden


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