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Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW)

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dc.contributor.authorHolden, Matthew T. G.
dc.contributor.authorLindsay, Jodi A.
dc.contributor.authorCorton, Craig
dc.contributor.authorQuail, Michael A.
dc.contributor.authorCockfield, Joshua D.
dc.contributor.authorPathak, Smriti
dc.contributor.authorBatra, Rahul
dc.contributor.authorParkhill, Julian
dc.contributor.authorBentley, Stephen D.
dc.contributor.authorEdgeworth, Jonathan D.
dc.date.accessioned2014-07-08T11:31:02Z
dc.date.available2014-07-08T11:31:02Z
dc.date.issued2010-02
dc.identifier.citationHolden , M T G , Lindsay , J A , Corton , C , Quail , M A , Cockfield , J D , Pathak , S , Batra , R , Parkhill , J , Bentley , S D & Edgeworth , J D 2010 , ' Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW) ' , Journal of Bacteriology , vol. 192 , no. 3 , pp. 888-892 . https://doi.org/10.1128/JB.01255-09en
dc.identifier.issn0021-9193
dc.identifier.otherPURE: 91765887
dc.identifier.otherPURE UUID: 9082b8b3-b5b6-4e14-b5c6-38b96f7b3d41
dc.identifier.otherWOS: 000273672000028
dc.identifier.otherScopus: 75149126472
dc.identifier.otherORCID: /0000-0002-4958-2166/work/60196461
dc.identifier.urihttp://hdl.handle.net/10023/4970
dc.descriptionThe Sanger Institute is core funded by the Wellcome Trust. Funding for the sequencing of the TW20 genome was provided by Guy’s and St. Thomas’ Charity. J.D.E. receives funding from the Department of Health via the NIHR comprehensive Biomedical Research Centre award to Guy’s and St Thomas’ NHS Foundation Trust in partnership with King’s College London.en
dc.description.abstractThe 3.1-Mb genome of an outbreak methicillin-resistant Staphylococcus aureus (MRSA) strain (TW20) contains evidence of recently acquired DNA, including two large regions ( 635 kb and 127 kb). The strain is resistant to a wide range of antibiotics, antiseptics, and heavy metals due to resistance genes encoded on mobile genetic elements and also mutations in housekeeping genes.
dc.format.extent5
dc.language.isoeng
dc.relation.ispartofJournal of Bacteriologyen
dc.rightsCopyright © 2010, American Society for Microbiology. All Rights Reserved. The authors have paid a fee to allow immediate free access to this articleen
dc.subjectNucleotide-sequenceen
dc.subjectEvolutionen
dc.subjectStrainen
dc.subjectIdentificationen
dc.subjectEpidermidisen
dc.subjectVirulenceen
dc.subjectProteinsen
dc.subjectCloneen
dc.subjectGeneen
dc.subjectChromosomeen
dc.subjectQR Microbiologyen
dc.subject.lccQRen
dc.titleGenome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW)en
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.contributor.institutionUniversity of St Andrews. Infection Groupen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doihttps://doi.org/10.1128/JB.01255-09
dc.description.statusPeer revieweden


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