Reading and language disorders : the importance of both quantity and quality
Date
04/04/2014Funder
Grant ID
n/a
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Abstract
Reading and language disorders are common childhood conditions that often co-occur with each other and with other neurodevelopmental impairments. There is strong evidence that disorders, such as dyslexia and Specific Language Impairment (SLI), have a genetic basis, but we expect the contributing genetic factors to be complex in nature. To date, only a few genes have been implicated in these traits. Their functional characterization has provided novel insight into the biology of neurodevelopmental disorders. However, the lack of biological markers and clear diagnostic criteria have prevented the collection of the large sample sizes required for well-powered genome-wide screens. One of the main challenges of the field will be to combine careful clinical assessment with high throughput genetic technologies within multidisciplinary collaborations.
Citation
Newbury , D F , Monaco , A P & Paracchini , S 2014 , ' Reading and language disorders : the importance of both quantity and quality ' , Genes , vol. 5 , no. 2 , pp. 285-309 . https://doi.org/10.3390/genes5020285
Publication
Genes
Status
Peer reviewed
ISSN
2073-4425Type
Journal article
Rights
© 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
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