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Quantification of tumour budding, lymphatic vessel density and invasion through image analysis in colorectal cancer

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dc.contributor.authorCaie, Peter David
dc.contributor.authorTurnbull, Arran K
dc.contributor.authorFarrington, Susan M
dc.contributor.authorOniscu, Anca
dc.contributor.authorHarrison, David J
dc.date.accessioned2014-06-12T11:31:02Z
dc.date.available2014-06-12T11:31:02Z
dc.date.issued2014-06-01
dc.identifier127012413
dc.identifierdcf0ef88-bf14-4d85-bc32-922501073f64
dc.identifier24885583
dc.identifier84904393656
dc.identifier000339025700001
dc.identifier.citationCaie , P D , Turnbull , A K , Farrington , S M , Oniscu , A & Harrison , D J 2014 , ' Quantification of tumour budding, lymphatic vessel density and invasion through image analysis in colorectal cancer ' , Journal of Translational Medicine , vol. 12 , no. 1 , 156 . https://doi.org/10.1186/1479-5876-12-156en
dc.identifier.issn1479-5876
dc.identifier.otherORCID: /0000-0002-0031-9850/work/60196561
dc.identifier.otherORCID: /0000-0001-9041-9988/work/64034351
dc.identifier.urihttps://hdl.handle.net/10023/4876
dc.descriptionFunding: University of St Andrews and NHS Lothian.en
dc.description.abstractTumour budding (TB), lymphatic vessel density (LVD) and lymphatic vessel invasion (LVI) have shown promise as prognostic factors in colorectal cancer (CRC) but reproducibility using conventional histopathology is challenging. We demonstrate image analysis methodology to quantify the histopathological features which could permit standardisation across institutes and aid risk stratification of Dukes B patients.
dc.format.extent22
dc.format.extent6111767
dc.language.isoeng
dc.relation.ispartofJournal of Translational Medicineen
dc.subjectImage analysisen
dc.subjectLymphatic vessel densityen
dc.subjectLymphatic vessel invasionen
dc.subjectTumour buddingen
dc.subjectColorectalen
dc.subjectPrognosisen
dc.subjectDigital pathologyen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subject.lccRC0254en
dc.titleQuantification of tumour budding, lymphatic vessel density and invasion through image analysis in colorectal canceren
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.identifier.doi10.1186/1479-5876-12-156
dc.description.statusPeer revieweden


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