Medicine: Recent submissions
Now showing items 196-200 of 205
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The inferior vena caval compression theory of hypotension in obstetric spinal anaesthesia: studies in normal and preeclamptic pregnancy, a literature review and revision of fundamental concepts
(2011) - ThesisThree clinical investigations together with a combined editorial and review of the cardiovascular physiology of spinal anaesthesia in normal and preeclamptic pregnancy form the basis of a thesis to be submitted for ... -
Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes.
(Spandidos, 2005) - Journal articlePhosphoinositol (PhoIns)-specific phospholipase C enzymes (PLCs) are central to the inositol lipid signaling pathways and contribute to intracellular Ca2+ release and protein kinase C activation. Five distinct classes of ... -
The effects of leptomycin B on HPV-infected cells
(University of St Andrews, 2008) - ThesisCervical cancer is a major cause of death in women and is strongly associated with infection by human papillomavirus (HPV). Integration of HPV is thought to form a key step in the formation of cancer, and is thought to ... -
A role for topoisomerase II alpha in chromosome damage in human cell lines
(University of St Andrews, 2010-06) - ThesisHuman response to ionising radiation (IR) shows a wide variation. This is most clearly seen in the radiation-response of cells as measured by frequencies of chromosomal aberrations. Different frequencies of IR-induced ... -
Cell cycle control and its modulation in HPV infected cells
(University of St Andrews, 2010-07) - ThesisA key effect of human papillomavirus (HPV) infection is to disrupt the normal cell cycle in order to subvert the cellular DNA replication machinery. Morphologically, condylomata induced by high and low risk HPV types cannot ...