The synthesis of natural and novel glucosinolates

dc.contributor.advisor	Botting, Nigel P.
dc.contributor.author	Cobb, Susan E.
dc.coverage.spatial	217	en_US
dc.date.accessioned	2013-06-07T13:51:29Z
dc.date.available	2013-06-07T13:51:29Z
dc.date.issued	2012
dc.identifier	uk.bl.ethos.574757
dc.identifier.uri	https://hdl.handle.net/10023/3634
dc.description.abstract	This thesis describes the synthesis of natural and novel glucosinolates 1.Chapter 1 gives an overview of glucosinolates, from isolation and biosynthesis to previous chemical syntheses. Chapter 2 describes an improved method for the formation of thiohydroximate bonds and its application over a variey of substrates. Chapter 3 focuses on exploring new chemistry on intact glucoinolates and details oxidative chemistry on an alkene containing side chain glucosinolate. Futhermore, the total synthesis of novel glucosinolates 150, 156 and 161 is illustrated.Chapter 4 describes a model study for the solid phase synthesis of glucosinolates. Finally experimental procedures for the compounds synthesised in the thesis are described in Chapter 5.	en_US
dc.language.iso	en	en_US
dc.publisher	University of St Andrews
dc.subject.lcc	QD325.C73
dc.subject.lcsh	Glucosinolates--Synthesis	en_US
dc.title	The synthesis of natural and novel glucosinolates	en_US
dc.type	Thesis	en_US
dc.type.qualificationlevel	Doctoral	en_US
dc.type.qualificationname	PhD Doctor of Philosophy	en_US
dc.publisher.institution	The University of St Andrews	en_US