Chemistry Theses
The School of Chemistry at St Andrews has a long history of research achievement stretching back to 1811. Research activity and strength spans most of the key areas and interfaces in the chemical sciences. Graduates have access to state-of-the-art facilities within Chemistry and in the associated interdisciplinary research centres.
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Recent Submissions
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Computational studies of biomolecules
(University of St Andrews, 2017-06-21) - ThesisIn modern drug discovery, lead discovery is a term used to describe the overall process from hit discovery to lead optimisation, with the goal being to identify drug candidates. This can be greatly facilitated by the use ... -
First syntheses of fluoromuscimols
(University of St Andrews, 2017-06-21) - ThesisChapter 1 provides a general introduction on the role of bioisosterism of fluorine aiming to improve the pharmacokinetics properties of lead compounds. GABAA receptors specifically, synaptic GABAA receptors, extrasynaptic ... -
Studies of some fused imidazole derivatives
(University of St Andrews, 1986) - ThesisThe main synthetic routes to benzimidazole N-oxides are outlined and some indication is given as to the current and potential pharmacological usefulness of such materials. A claim that 4-methyl-2-nitrophenylglycine is ... -
Intermediates and enzymes involved in fluorometabolite biosynthesis in Streptomyces cattleya
(University of St Andrews, 2006) - ThesisEnzymatic halogenation occurs during the biosynthesis of more than 4,000 natural products. The presence of fluorinated natural products is much less common, with only 13 reported to date. The bacterium Streptomyces ... -
Iodine-promoted activation of sulfur-based leaving groups in glycosylation reactions
(University of St Andrews, 2000) - ThesisFurther to previous work by the Field group on the iodine-mediated activation of benzyl ether-protected ('armed') thiogalactosides, a variety of ester-protected ('disarmed') β-D- thiogalactoside derivatives containing ...
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