The School of Chemistry at St Andrews has a long history of research achievement stretching back to 1811. Research activity and strength spans most of the key areas and interfaces in the chemical sciences. Graduates have access to state-of-the-art facilities within Chemistry and in the associated interdisciplinary research centres.

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Recent Submissions

  • Selective and catalytic carbon dioxide and heteroallene activation mediated by cerium N-heterocyclic carbene complexes 

    Arnold, Polly L.; Kerr, Ryan W. F.; Weetman, Catherine; Docherty, Scott R.; Rieb, Julia; Cruickshank, Faye L.; Wang, Kai; Jandl, Christian; McMullon, Max W.; Pöthig, Alexander; Kühn, Fritz E.; Smith, Andrew D. (2018-09-10) - Journal article
    A series of rare earth complexes of the form Ln(LR)3 supported by bidentate ortho-aryloxide–NHC ligands are reported (LR = 2-O-3,5-tBu2-C6H2(1-C{N(CH)2N(R)})); R = iPr, tBu, Mes; Ln = Ce, Sm, Eu). The cerium complexes ...
  • A flow platform for degradation-free CuAAC bioconjugation 

    Hatit, Marine Z. C.; Reichenbach, Linus F.; Tobin, John M.; Vilela, Filipe; Burley, Glenn A.; Watson, Allan J. B. (2018-10-01) - Journal article
    The Cu-catalyzed azide-alkyne cycloaddition (CuAAC) reaction is a cornerstone method for the ligation of biomolecules. However, undesired Cu-mediated oxidation and Cu-contamination in bioconjugates limits biomedical utility. ...
  • A new route to α,ω-diamines from hydrogenation of dicarboxylic acids and their derivatives in the presence of amines 

    Shi, Yiping; Kamer, Paulus Clemens Jozef; Cole-Hamilton, David John (2017-10-11) - Journal article
    A new and selective route for the synthesis of polymer precursors, primary diamines or N-substituted diamines, from dicarboxylic acids, diesters, diamides and diols using a Ru/ triphos catalyst is reported. Excellent ...
  • Versatile pyrolytic synthesis of fused polycyclic heteroaromatic compounds 

    Aitken, R Alan; Garnett, Alasdair N. (2017-11) - Journal article
    Thirty-six new stabilised phosphonium ylides designed to undergo thermal loss of Ph3PO and radical domino cyclisation have been prepared and are generally found to undergo the desired reaction under flash vacuum pyrolysis ...
  • Molecular mechanism of activation of human musk receptors OR5AN1 and OR1A1 by (R)-muscone and diverse other musk-smelling compounds 

    Ahmed, Lucky; Zhang, Yuetian; Block, Eric; Buehl, Michael; Corr, Michael J.; Cormanich, Rodrigo A.; Gundala, Sivaji; Matsunami, Hiroaki; O'Hagan, David; Ozbil, Mehmet; Pan, Yi; Sekharan, Sivakumar; Ten, Nicholas; Wang, Mingan; Yang, Mingyan; Zhang, Qingzhi; Zhang, Ruina; Batista, Victor; Zhuang, Hanyi (2018-04-24) - Journal item
    Understanding olfaction at the molecular level is challenging due to lack of crystallographic models of odorant receptors (ORs). To better understand the molecular mechanism of OR activation, we focused on chiral (R)-muscone ...

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