Chemistry (School of)
The School of Chemistry at St Andrews has a long history of research achievement stretching back to 1811. Research activity and strength spans most of the key areas and interfaces in the chemical sciences. Graduates have access to state-of-the-art facilities within Chemistry and in the associated interdisciplinary research centres.
For more information please visit the School of Chemistry home page.
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(University of St Andrews, 2020-06) - ThesisThe thesis focuses on the synthesis of novel fluorinated cycloalkanes and their polar properties. Chapter 2 describes the synthesis of all cis-1,2,3,4-tetrafluorocyclopentane and its deuterated isotopomer. They were ...
Genome sequencing, analysis, heterologous expression and genetic modification of antibiotic encoding biosynthetic gene clusters (University of St Andrews, 2020-06) - ThesisMicrobial natural products represent an unparalleled starting point for drug discovery. This thesis therefore focuses on microbial natural products, and the biosynthetic gene clusters (BGCs) that encode them. A series ...
Developing genetic and chemical tools for the GenoChemetic generation of natural product analogues (University of St Andrews, 2020-06) - ThesisNatural products provide one of the corner stones of both modern and historical medicine, contributing towards over 65 % of new FDA approved drugs that entered clinical trials between 1981 and 2014. It is partly down to ...
(University of St Andrews, 2020-06-24) - ThesisThis thesis details the development of enantioselective, isothiourea-catalysed, acyl-transfer methodology for the synthesis of atropisomers. Chapter 1 aims to introduce organocatalysis in the context of the current ...
Insights into the structure and reactivity of the biopolymer lignin using diffusion ordered spectroscopy and synthetic model studies (University of St Andrews, 2020-06-24) - Thesis