Now showing items 1-5 of 682

    • Towards mitochondrial targeting for the treatment of Alzheimer's Disease 

      Abdul Razzak, Rana (University of St Andrews, 2019-06-26) - Thesis
      Nanoparticles (NPs) have emerged as a promising approach to overcoming biological barriers imposed by the human body. Polymeric NPs offer a superior synthetic flexibility and advances in polymerization chemistries have ...
    • Preparation, characterisation and application of ordered mesoporous materials 

      Sakina, Farzeen (University of St Andrews, 2019-06-26) - Thesis
      The history of ordered mesoporous materials starts with the discovery of MCM-41(Mobil Composition of Matter-41) in 1992 using an organic template as structure directing agent. Mesoporous materials have not only proved ...
    • Complementary hydrazone-based dynamic covalent nanoparticles 

      Marro, Nicolas (University of St Andrews, 2019-06-26) - Thesis
      The extraordinary and unique properties exhibited by monolayer-stabilised metal nanoparticles suggest exciting potential applications. Surface-bound molecules stabilize the material in colloidal form, but also define a ...
    • The design of acyl modified co-enzyme-A ester analogues as enzyme inhibitors 

      Rubanu, Maria Grazia (University of St Andrews, 2019-12-03) - Thesis
      This thesis is focused on the design and synthesis of analogues of thioesters of Co-enzyme A which are involved in many important biosynthetic pathways. Acetyl-CoA is converted into citrate by citrate synthase in the ...
    • Toxic gas adsorption and water stability in metal-organic frameworks 

      McHugh, Lauren Nicole (University of St Andrews, 2019-12-03) - Thesis
      This thesis largely focuses on the development of water stable metal-organic frameworks (MOFs) for the removal of toxic industrial chemicals (TICs) from airstreams. The aim of the research is to investigate the water ...