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Synthesis of phosphonate and phostone analogues of ribose-1-phosphates

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dc.contributor.authorNasomjai, Pitak
dc.contributor.authorO'Hagan, David
dc.contributor.authorSlawin, Alexandra M. Z.
dc.date.accessioned2013-03-27T17:01:03Z
dc.date.available2013-03-27T17:01:03Z
dc.date.issued2009-07-27
dc.identifier16814101
dc.identifier5a1c3386-7370-4440-b032-ca485d70bdac
dc.identifier000270222500001
dc.identifier75949101935
dc.identifier.citationNasomjai , P , O'Hagan , D & Slawin , A M Z 2009 , ' Synthesis of phosphonate and phostone analogues of ribose-1-phosphates ' , Beilstein Journal of Organic Chemistry , vol. 5 , 37 . https://doi.org/10.3762/bjoc.5.37en
dc.identifier.issn1860-5397
dc.identifier.otherORCID: /0000-0002-9527-6418/work/56861453
dc.identifier.otherORCID: /0000-0002-0510-5552/work/68281220
dc.identifier.urihttps://hdl.handle.net/10023/3444
dc.description.abstractThe synthesis of phosphonate analogues of ribose-1-phosphate and 5-fluoro-5-deoxyribose-1-phosphate is described. Preparations of both the alpha- and beta-phosphonate anomers are reported for the ribose and 5-fluoro-5-deoxyribose series and a synthesis of the corresponding cyclic phostones of each alpha-ribose is also reported. These compounds have been prepared as tools to probe the details of fluorometabolism in S. cattleya.
dc.format.extent7
dc.format.extent373671
dc.language.isoeng
dc.relation.ispartofBeilstein Journal of Organic Chemistryen
dc.subject5-fluoro-5-deoxyribose-1-phosphateen
dc.subjectfluorometabolite biosynthesisen
dc.subjectphosphonatesen
dc.subjectphostoneen
dc.subjectribose-1-phosphateen
dc.subjectBiosynthesisen
dc.subjectFluorinaseen
dc.subjectAciden
dc.subjectQD Chemistryen
dc.subject.lccQDen
dc.titleSynthesis of phosphonate and phostone analogues of ribose-1-phosphatesen
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Chemistryen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.contributor.institutionUniversity of St Andrews. EaSTCHEMen
dc.identifier.doi10.3762/bjoc.5.37
dc.description.statusPeer revieweden


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