Synthesis of phosphonate and phostone analogues of ribose-1-phosphates
Abstract
The synthesis of phosphonate analogues of ribose-1-phosphate and 5-fluoro-5-deoxyribose-1-phosphate is described. Preparations of both the alpha- and beta-phosphonate anomers are reported for the ribose and 5-fluoro-5-deoxyribose series and a synthesis of the corresponding cyclic phostones of each alpha-ribose is also reported. These compounds have been prepared as tools to probe the details of fluorometabolism in S. cattleya.
Citation
Nasomjai , P , O'Hagan , D & Slawin , A M Z 2009 , ' Synthesis of phosphonate and phostone analogues of ribose-1-phosphates ' , Beilstein Journal of Organic Chemistry , vol. 5 , 37 . https://doi.org/10.3762/bjoc.5.37
Publication
Beilstein Journal of Organic Chemistry
Status
Peer reviewed
ISSN
1860-5397Type
Journal article
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