Extending the utility of [Pd(NHC)(cinnamyl)Cl] precatalysts : Direct arylation of heterocycles
Abstract
The use of [Pd(NHC)(cinnamyl)Cl] precatalysts in the direct arylation of heterocycles has been investigated. Among four different precatalysts, [Pd(SIPr)(cinnamyl)Cl] proved to be the most efficient promoter of the reaction. The C–H functionalization of sulfuror nitrogen-containing heterocycles has been achieved at low catalyst loadings. These catalyst charges range from 0.1 to 0.01 mol % palladium.
Citation
Martin , A , Chartoire , A R G , Slawin , A M Z & Nolan , S P 2012 , ' Extending the utility of [Pd(NHC)(cinnamyl)Cl] precatalysts : Direct arylation of heterocycles ' , Beilstein Journal of Organic Chemistry , vol. 8 , pp. 1637-1643 . https://doi.org/10.3762/bjoc.8.187
Publication
Beilstein Journal of Organic Chemistry
Status
Peer reviewed
ISSN
1860-5397Type
Journal article
Collections
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