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Temporal genomics in Hawaiian crickets reveals compensatory intragenomic coadaptation during adaptive evolution
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dc.contributor.author | Zhang, Xiao | |
dc.contributor.author | Blaxter, Mark | |
dc.contributor.author | Wood, Jonathan M.D. | |
dc.contributor.author | Tracey, Alan | |
dc.contributor.author | McCarthy, Shane | |
dc.contributor.author | Thorpe, Peter | |
dc.contributor.author | Rayner, Jack G. | |
dc.contributor.author | Zhang, Shangzhe | |
dc.contributor.author | Sikkink, Kirstin L. | |
dc.contributor.author | Balenger, Susan L. | |
dc.contributor.author | Bailey, Nathan W. | |
dc.date.accessioned | 2024-07-03T11:30:27Z | |
dc.date.available | 2024-07-03T11:30:27Z | |
dc.date.issued | 2024-06-12 | |
dc.identifier | 304443928 | |
dc.identifier | 95f6443c-9e5c-4575-adaf-1f90f087d754 | |
dc.identifier | 85195925877 | |
dc.identifier | 38866741 | |
dc.identifier.citation | Zhang , X , Blaxter , M , Wood , J M D , Tracey , A , McCarthy , S , Thorpe , P , Rayner , J G , Zhang , S , Sikkink , K L , Balenger , S L & Bailey , N W 2024 , ' Temporal genomics in Hawaiian crickets reveals compensatory intragenomic coadaptation during adaptive evolution ' , Nature Communications , vol. 15 , no. 1 , 5001 . https://doi.org/10.1038/s41467-024-49344-4 | en |
dc.identifier.issn | 2041-1723 | |
dc.identifier.other | ORCID: /0000-0003-3531-7756/work/163120538 | |
dc.identifier.other | ORCID: /0000-0003-2064-4287/work/163120750 | |
dc.identifier.uri | https://hdl.handle.net/10023/30082 | |
dc.description | This study was supported with funding from the UK Natural Environment Research Council to N.W.B. (NE/T000619/1, NE/T014806/1, NE/L011255/1) and M.B. (NE/W001519/1). We are grateful for bioinformatics support from Iain Milne and the use of the UK\u2019s Crop Diversity Bioinformatics HPC, funded by the UK Biotechnology and Biological Sciences Research Council (BB/S019669/1), as well as the St Andrews Bioinformatics Unit, funded by a Wellcome Trust ISSF award (105621/Z/14/Z). | en |
dc.description.abstract | Theory predicts that compensatory genetic changes reduce negative indirect effects of selected variants during adaptive evolution, but evidence is scarce. Here, we test this in a wild population of Hawaiian crickets using temporal genomics and a high-quality chromosome-level cricket genome. In this population, a mutation, flatwing, silences males and rapidly spread due to an acoustically-orienting parasitoid. Our sampling spanned a social transition during which flatwing fixed and the population went silent. We find long-range linkage disequilibrium around the putative flatwing locus was maintained over time, and hitchhiking genes had functions related to negative flatwing-associated effects. We develop a combinatorial enrichment approach using transcriptome data to test for compensatory, intragenomic coevolution. Temporal changes in genomic selection were distributed genome-wide and functionally associated with the population’s transition to silence, particularly behavioural responses to silent environments. Our results demonstrate how ‘adaptation begets adaptation’; changes to the sociogenetic environment accompanying rapid trait evolution can generate selection provoking further, compensatory adaptation. | |
dc.format.extent | 3646146 | |
dc.language.iso | eng | |
dc.relation.ispartof | Nature Communications | en |
dc.subject | Chemistry(all) | en |
dc.subject | Biochemistry, Genetics and Molecular Biology(all) | en |
dc.subject | Physics and Astronomy(all) | en |
dc.subject | DAS | en |
dc.title | Temporal genomics in Hawaiian crickets reveals compensatory intragenomic coadaptation during adaptive evolution | en |
dc.type | Journal article | en |
dc.contributor.sponsor | NERC | en |
dc.contributor.sponsor | NERC | en |
dc.contributor.sponsor | NERC | en |
dc.contributor.sponsor | The Wellcome Trust | en |
dc.contributor.institution | University of St Andrews. School of Biology | en |
dc.contributor.institution | University of St Andrews. School of Medicine | en |
dc.contributor.institution | University of St Andrews. Centre for Biological Diversity | en |
dc.contributor.institution | University of St Andrews. Institute of Behavioural and Neural Sciences | en |
dc.contributor.institution | University of St Andrews. St Andrews Bioinformatics Unit | en |
dc.identifier.doi | https://doi.org/10.1038/s41467-024-49344-4 | |
dc.description.status | Peer reviewed | en |
dc.identifier.grantnumber | NE/T000619/1 | en |
dc.identifier.grantnumber | NE/T014806/1 | en |
dc.identifier.grantnumber | NE/L011255/1 | en |
dc.identifier.grantnumber | 105621/Z/14/Z | en |
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