Files in this item
Multi-layered genome defences in bacteria
Item metadata
dc.contributor.author | Agapov, Aleksei | |
dc.contributor.author | Baker, Kate S. | |
dc.contributor.author | Bedekar, Paritosh | |
dc.contributor.author | Bhatia, Rama P. | |
dc.contributor.author | Blower, Tim R. | |
dc.contributor.author | Brockhurst, Michael A. | |
dc.contributor.author | Brown, Cooper | |
dc.contributor.author | Chong, Charlotte E. | |
dc.contributor.author | Fothergill, Joanne L. | |
dc.contributor.author | Graham, Shirley | |
dc.contributor.author | Hall, James PJ | |
dc.contributor.author | Maestri, Alice | |
dc.contributor.author | McQuarrie, Stuart | |
dc.contributor.author | Olina, Anna | |
dc.contributor.author | Pagliara, Stefano | |
dc.contributor.author | Recker, Mario | |
dc.contributor.author | Richmond, Anna | |
dc.contributor.author | Shaw, Steven J. | |
dc.contributor.author | Szczelkun, Mark D. | |
dc.contributor.author | Taylor, Tiffany B. | |
dc.contributor.author | van Houte, Stineke | |
dc.contributor.author | Went, Sam C. | |
dc.contributor.author | Westra, Edze R. | |
dc.contributor.author | White, Malcolm F. | |
dc.contributor.author | Wright, Rosanna | |
dc.date.accessioned | 2024-05-30T10:30:13Z | |
dc.date.available | 2024-05-30T10:30:13Z | |
dc.date.issued | 2024-04 | |
dc.identifier | 302155980 | |
dc.identifier | a8de3f85-df72-4d40-b245-9eb1e2835fbc | |
dc.identifier | 85185407446 | |
dc.identifier | 38368839 | |
dc.identifier.citation | Agapov , A , Baker , K S , Bedekar , P , Bhatia , R P , Blower , T R , Brockhurst , M A , Brown , C , Chong , C E , Fothergill , J L , Graham , S , Hall , J PJ , Maestri , A , McQuarrie , S , Olina , A , Pagliara , S , Recker , M , Richmond , A , Shaw , S J , Szczelkun , M D , Taylor , T B , van Houte , S , Went , S C , Westra , E R , White , M F & Wright , R 2024 , ' Multi-layered genome defences in bacteria ' , Current Opinion in Microbiology , vol. 78 , 102436 . https://doi.org/10.1016/j.mib.2024.102436 | en |
dc.identifier.issn | 1369-5274 | |
dc.identifier.uri | https://hdl.handle.net/10023/29949 | |
dc.description | This work was supported by a grant from the Biotechnology and Biological Sciences Research Council sLoLa BB/X003051/1 , awarded to KB, TRB, MB, JF, JH, SP, MR, MDS, TBT, SVH, ERW and MFW. JH is supported by an MRC Career Development Award ( MR/W02666X/1 ). AA is supported by UK Research and Innovation under the UK government’s Horizon Europe funding guarantee ( EP/Y020308/1 ). | en |
dc.description.abstract | Bacteria have evolved a variety of defence mechanisms to protect against mobile genetic elements, including restriction-modification systems and CRISPR–Cas. In recent years, dozens of previously unknown defence systems (DSs) have been discovered. Notably, diverse DSs often coexist within the same genome, and some co-occur at frequencies significantly higher than would be expected by chance, implying potential synergistic interactions. Recent studies have provided evidence of defence mechanisms that enhance or complement one another. Here, we review the interactions between DSs at the mechanistic, regulatory, ecological and evolutionary levels. | |
dc.format.extent | 10 | |
dc.format.extent | 3327863 | |
dc.language.iso | eng | |
dc.relation.ispartof | Current Opinion in Microbiology | en |
dc.subject | Microbiology | en |
dc.subject | Microbiology (medical) | en |
dc.subject | Infectious Diseases | en |
dc.subject | SDG 3 - Good Health and Well-being | en |
dc.subject | TBC | en |
dc.title | Multi-layered genome defences in bacteria | en |
dc.type | Journal item | en |
dc.contributor.sponsor | BBSRC | en |
dc.contributor.institution | University of St Andrews. School of Biology | en |
dc.contributor.institution | University of St Andrews. Biomedical Sciences Research Complex | en |
dc.contributor.institution | University of St Andrews. St Andrews Bioinformatics Unit | en |
dc.identifier.doi | https://doi.org/10.1016/j.mib.2024.102436 | |
dc.description.status | Peer reviewed | en |
dc.identifier.grantnumber | BB/X003051/1 | en |
This item appears in the following Collection(s)
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.