Show simple item record

Files in this item

Thumbnail

Item metadata

dc.contributor.authorFritzen, Remi
dc.contributor.authorDavies, Amy
dc.contributor.authorVeenhuizen, Miriam
dc.contributor.authorCampbell, Matthew
dc.contributor.authorPitt, Samantha J.
dc.contributor.authorAjjan, Ramzi A.
dc.contributor.authorStewart, Alan J.
dc.date.accessioned2023-05-18T09:30:12Z
dc.date.available2023-05-18T09:30:12Z
dc.date.issued2023-05-17
dc.identifier286018895
dc.identifier13854a30-c594-4676-bc48-3124cc6a9770
dc.identifier85160329060
dc.identifier.citationFritzen , R , Davies , A , Veenhuizen , M , Campbell , M , Pitt , S J , Ajjan , R A & Stewart , A J 2023 , ' Magnesium deficiency and cardiometabolic disease ' , Nutrients , vol. 15 , no. 10 , 2355 . https://doi.org/10.3390/nu15102355en
dc.identifier.issn2072-6643
dc.identifier.otherORCID: /0000-0003-2257-1595/work/135454734
dc.identifier.otherORCID: /0000-0003-4580-1840/work/135454982
dc.identifier.otherORCID: /0000-0003-3457-8364/work/135455081
dc.identifier.urihttps://hdl.handle.net/10023/27641
dc.descriptionFunding: R.F. is supported by the Biological and Biotechnological Sciences Research Council.en
dc.description.abstractMagnesium (Mg2+) has many physiological functions within the body. These include important roles in maintaining cardiovascular functioning, where it contributes to the regulation of cardiac excitation–contraction coupling, endothelial functioning and haemostasis. The haemostatic roles of Mg2+ impact upon both the protein and cellular arms of coagulation. In this review, we examine how Mg2+ homeostasis is maintained within the body and highlight the various molecular roles attributed to Mg2+ in the cardiovascular system. In addition, we describe how nutritional and/or disease-associated magnesium deficiency, seen in some metabolic conditions, has the potential to influence cardiac and vascular outcomes. Finally, we also examine the potential for magnesium supplements to be employed in the prevention and treatment of cardiovascular disorders and in the management of cardiometabolic health.
dc.format.extent19
dc.format.extent1009759
dc.language.isoeng
dc.relation.ispartofNutrientsen
dc.subjectCardiovascular diseaseen
dc.subjectMagnesiumen
dc.subjectMetal ion dyshomeostasisen
dc.subjectNutrient deficiencyen
dc.subjectSupplementationen
dc.subjectQH301 Biologyen
dc.subjectRA0421 Public health. Hygiene. Preventive Medicineen
dc.subjectT-DASen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectMCCen
dc.subject.lccQH301en
dc.subject.lccRA0421en
dc.titleMagnesium deficiency and cardiometabolic diseaseen
dc.typeJournal articleen
dc.contributor.sponsorBBSRCen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.contributor.institutionUniversity of St Andrews. Sir James Mackenzie Institute for Early Diagnosisen
dc.contributor.institutionUniversity of St Andrews. Centre for Biophotonicsen
dc.contributor.institutionUniversity of St Andrews. Cellular Medicine Divisionen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.contributor.institutionUniversity of St Andrews. Institute of Behavioural and Neural Sciencesen
dc.identifier.doi10.3390/nu15102355
dc.description.statusPeer revieweden
dc.identifier.urlhttps://www.mdpi.com/2072-6643/15/10/2355en
dc.identifier.grantnumberBB/V014684/1en


This item appears in the following Collection(s)

Show simple item record