Manganese catalysed enantioselective hydrogenation of in-situ-synthesised imines : efficient asymmetric synthesis of amino-indane derivatives
MetadataShow full item record
A manganese catalyst of a facially coordinating P,N,N ligand catalyses the hydrogenation of imines derived from indanone derivatives with high enantioselectivity. There is no requirement for an activating group and imines can be generated in situ. The selectivity can be rationalised by DFT calculations.
Oates , C , Goodfellow , A S , Buehl , M & Clarke , M 2023 , ' Manganese catalysed enantioselective hydrogenation of in-situ -synthesised imines : efficient asymmetric synthesis of amino-indane derivatives ' , Green Chemistry , vol. 25 , no. 10 , pp. 3864-3868 . https://doi.org/10.1039/D3GC00399J
Copyright The author(s). This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
DescriptionFunding: The authors would like to thank the University of St Andrews, and the EPSRC Centre for Doctoral Training in Critical Resource Catalysis (CRITICAT) for financial support [Ph.D. studentship to CO; Grant code: EP/L016419/1], and the EaSI-CAT programme PhD studentship to AG. They thank Solvias for the gift of chiral chemicals.
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.