Manganese catalysed enantioselective hydrogenation of in-situ-synthesised imines : efficient asymmetric synthesis of amino-indane derivatives

Thumbnail
View/Open
Oates_2023_GC_Manganese_catalysed_CC.pdf (570.8Kb)
Date
21/05/2023
Author
Funder
Grant ID
EP/L016419/1
Keywords
DAS
MCC
Metadata
Show full item record
Abstract
A manganese catalyst of a facially coordinating P,N,N ligand catalyses the hydrogenation of imines derived from indanone derivatives with high enantioselectivity. There is no requirement for an activating group and imines can be generated in situ. The selectivity can be rationalised by DFT calculations.
Citation
Oates , C , Goodfellow , A S , Buehl , M & Clarke , M 2023 , ' Manganese catalysed enantioselective hydrogenation of in-situ -synthesised imines : efficient asymmetric synthesis of amino-indane derivatives ' , Green Chemistry , vol. 25 , no. 10 , pp. 3864-3868 . https://doi.org/10.1039/D3GC00399J
Publication
Green Chemistry
Status
Peer reviewed
DOI
https://doi.org/10.1039/D3GC00399J
ISSN
1463-9262
Type
Journal article
Rights
Copyright The author(s). This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Description
Funding: The authors would like to thank the University of St Andrews, and the EPSRC Centre for Doctoral Training in Critical Resource Catalysis (CRITICAT) for financial support [Ph.D. studentship to CO; Grant code: EP/L016419/1], and the EaSI-CAT programme PhD studentship to AG. They thank Solvias for the gift of chiral chemicals.
Collections
URI
http://hdl.handle.net/10023/27597

Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.