Chiropterans are a hotspot for horizontal transfer of DNA transposons in mammalia
Abstract
Horizontal transfer of transposable elements (TEs) is an important mechanism contributing to genetic diversity and innovation. Bats (order Chiroptera) have repeatedly been shown to experience horizontal transfer of TEs at what appears to be a high rate compared with other mammals. We investigated the occurrence of horizontally transferred (HT) DNA transposons involving bats. We found over 200 putative HT elements within bats; 16 transposons were shared across distantly related mammalian clades, and 2 other elements were shared with a fish and two lizard species. Our results indicate that bats are a hotspot for horizontal transfer of DNA transposons. These events broadly coincide with the diversification of several bat clades, supporting the hypothesis that DNA transposon invasions have contributed to genetic diversification of bats.
Citation
Paulat , N S , Storer , J M , Moreno-Santillán , D D , Osmanski , A B , Sullivan , K A M , Grimshaw , J R , Korstian , J , Halsey , M , Garcia , C J , Crookshanks , C , Roberts , J , Smit , A F A , Hubley , R , Rosen , J , Teeling , E C , Vernes , S C , Myers , E , Pippel , M , Brown , T , Hiller , M , Consortium , Z , Rojas , D , Dávalos , L M , Lindblad-Toh , K , Karlsson , E K & Ray , D A 2023 , ' Chiropterans are a hotspot for horizontal transfer of DNA transposons in mammalia ' , Molecular Biology and Evolution , vol. 40 , no. 5 , msad092 . https://doi.org/10.1093/molbev/msad092
Publication
Molecular Biology and Evolution
Status
Peer reviewed
ISSN
1537-1719Type
Journal article
Rights
Copyright © The Author(s) 2023. Published by Oxford University Press on behalf of Society for Molecular Biology and Evolution. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Description
Funding: This project was supported by the National Science Foundation (grant numbers DEB 1838283 and IOS 2032006 to D.M.-S. and Dav.R. and DEB 1838273 and DGE 1633299 to L.D.), National Institutes of Health (grant numbers R01HG002939 and U24HG010136 to J.S., R.H., A.F.A.S., and Je.R.), NHGRI (grant number R01HG008742 to Z.C.), Irish Research Council (grant number IRCLA/ 2017/58 to E.T.), Science Foundation Ireland (grant number 19/FFP/6790 to E.T.), Max Planck Research Group awarded by the Max Planck Gesellschaft to S.V., Human Frontiers Science Program (grant number RGP0058/2016 to S.V.), UK Research and Innovation (grant number MR/T021985/1 to S.V.), and the Swedish Research Council Distinguished Professor Award to K.L.-T.Collections
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