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Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care : I-MOVE-COVID-19 project, Europe, December 2020 to May 2021

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dc.contributor.authorKissling, Esther
dc.contributor.authorHooiveld, Mariette
dc.contributor.authorSandonis Martín, Virginia
dc.contributor.authorMartínez-Baz, Iván
dc.contributor.authorWilliam, Naoma
dc.contributor.authorVilcu, Ana Maria
dc.contributor.authorMazagatos, Clara
dc.contributor.authorDomegan, Lisa
dc.contributor.authorde Lusignan, Simon
dc.contributor.authorMeijer, Adam
dc.contributor.authorMachado, Ausenda
dc.contributor.authorBrytting, Mia
dc.contributor.authorCasado, Itziar
dc.contributor.authorMurray, Josephine L.K.
dc.contributor.authorBelhillil, Sylvie
dc.contributor.authorLarrauri, Amparo
dc.contributor.authorO'Donnell, Joan
dc.contributor.authorTsang, Ruby
dc.contributor.authorde Lange, Marit
dc.contributor.authorRodrigues, Ana Paula
dc.contributor.authorRiess, Maximilian
dc.contributor.authorCastilla, Jesús
dc.contributor.authorHamilton, Mark
dc.contributor.authorFalchi, Alessandra
dc.contributor.authorPozo, Francisco
dc.contributor.authorDunford, Linda
dc.contributor.authorCogdale, Jade
dc.contributor.authorJansen, Tessa
dc.contributor.authorGuiomar, Raquel
dc.contributor.authorEnkirch, Theresa
dc.contributor.authorBurgui, Cristina
dc.contributor.authorSigerson, Debbie
dc.contributor.authorBlanchon, Thierry
dc.contributor.authorMartínez Ochoa, Eva María
dc.contributor.authorConnell, Jeff
dc.contributor.authorEllis, Joanna
dc.contributor.authorvan Gageldonk-Lafeber, Rianne
dc.contributor.authorKislaya, Irina
dc.contributor.authorRose, Angela MC
dc.contributor.authorValenciano, Marta
dc.contributor.authorI-MOVE-COVID-19 primary care study team
dc.date.accessioned2022-09-23T11:30:14Z
dc.date.available2022-09-23T11:30:14Z
dc.date.issued2021-07-22
dc.identifier280689252
dc.identifier2a8ba9c1-abcd-4a74-9196-0b4dbcf0542c
dc.identifier85112153857
dc.identifier34296676
dc.identifier.citationKissling , E , Hooiveld , M , Sandonis Martín , V , Martínez-Baz , I , William , N , Vilcu , A M , Mazagatos , C , Domegan , L , de Lusignan , S , Meijer , A , Machado , A , Brytting , M , Casado , I , Murray , J L K , Belhillil , S , Larrauri , A , O'Donnell , J , Tsang , R , de Lange , M , Rodrigues , A P , Riess , M , Castilla , J , Hamilton , M , Falchi , A , Pozo , F , Dunford , L , Cogdale , J , Jansen , T , Guiomar , R , Enkirch , T , Burgui , C , Sigerson , D , Blanchon , T , Martínez Ochoa , E M , Connell , J , Ellis , J , van Gageldonk-Lafeber , R , Kislaya , I , Rose , A MC , Valenciano , M & I-MOVE-COVID-19 primary care study team 2021 , ' Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care : I-MOVE-COVID-19 project, Europe, December 2020 to May 2021 ' , Eurosurveillance , vol. 26 , no. 29 , 2100670 . https://doi.org/10.2807/1560-7917.ES.2021.26.29.2100670en
dc.identifier.issn1025-496X
dc.identifier.otherORCID: /0000-0002-1511-7944/work/116910274
dc.identifier.urihttps://hdl.handle.net/10023/26062
dc.descriptionThis project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673.en
dc.description.abstractWe measured COVID-19 vaccine effectiveness (VE) against symptomatic SARS-CoV-2 infection at primary care/outpatient level among adults ≥ 65 years old using a multicentre test-negative design in eight European countries. We included 592 SARS-CoV-2 cases and 4,372 test-negative controls in the main analysis. The VE was 62% (95% CI: 45-74) for one dose only and 89% (95% CI: 79-94) for complete vaccination. COVID-19 vaccines provide good protection against COVID-19 presentation at primary care/outpatient level, particularly among fully vaccinated individuals.
dc.format.extent7
dc.format.extent149080
dc.language.isoeng
dc.relation.ispartofEurosurveillanceen
dc.subjectCOVID-19en
dc.subjectEuropeen
dc.subjectMulticentre studyen
dc.subjectSARS-CoV-2en
dc.subjectTest-negative designen
dc.subjectVaccine effectivenessen
dc.subjectQR355 Virologyen
dc.subjectRA0421 Public health. Hygiene. Preventive Medicineen
dc.subjectRM Therapeutics. Pharmacologyen
dc.subjectVirologyen
dc.subjectEpidemiologyen
dc.subjectPublic Health, Environmental and Occupational Healthen
dc.subject3rd-DASen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectNISen
dc.subject.lccQR355en
dc.subject.lccRA0421en
dc.subject.lccRMen
dc.titleVaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care : I-MOVE-COVID-19 project, Europe, December 2020 to May 2021en
dc.typeJournal articleen
dc.contributor.institutionUniversity of St Andrews. School of Medicineen
dc.contributor.institutionUniversity of St Andrews. Education Divisionen
dc.identifier.doi10.2807/1560-7917.ES.2021.26.29.2100670
dc.description.statusPeer revieweden


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