Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care : I-MOVE-COVID-19 project, Europe, December 2020 to May 2021

We measured COVID-19 vaccine effectiveness (VE) against symptomatic SARS-CoV-2 infection at primary care/outpatient level among adults ≥ 65 years old using a multicentre test-negative design in eight European countries. We included 592 SARS-CoV-2 cases and 4,372 test-negative controls in the main analysis. The VE was 62% (95% CI: 45-74) for one dose only and 89% (95% CI: 79-94) for complete vaccination. COVID-19 vaccines provide good protection against COVID-19 presentation at primary care/outpatient level, particularly among fully vaccinated individuals.

Citation

Kissling , E , Hooiveld , M , Sandonis Martín , V , Martínez-Baz , I , William , N , Vilcu , A M , Mazagatos , C , Domegan , L , de Lusignan , S , Meijer , A , Machado , A , Brytting , M , Casado , I , Murray , J L K , Belhillil , S , Larrauri , A , O'Donnell , J , Tsang , R , de Lange , M , Rodrigues , A P , Riess , M , Castilla , J , Hamilton , M , Falchi , A , Pozo , F , Dunford , L , Cogdale , J , Jansen , T , Guiomar , R , Enkirch , T , Burgui , C , Sigerson , D , Blanchon , T , Martínez Ochoa , E M , Connell , J , Ellis , J , van Gageldonk-Lafeber , R , Kislaya , I , Rose , A MC , Valenciano , M & I-MOVE-COVID-19 primary care study team 2021 , ' Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care : I-MOVE-COVID-19 project, Europe, December 2020 to May 2021 ' , Eurosurveillance , vol. 26 , no. 29 , 2100670 . https://doi.org/10.2807/1560-7917.ES.2021.26.29.2100670

Publication

Eurosurveillance

Status

Peer reviewed

DOI

https://doi.org/10.2807/1560-7917.ES.2021.26.29.2100670

ISSN

1025-496X

Type

Journal article

Rights

This article is copyright of the authors or their affiliated institutions, 2021. This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence and indicate if changes were made.

Description

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673.

Collections

University of St Andrews Research

URI

http://hdl.handle.net/10023/26062

St Andrews Research Repository