Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care : I-MOVE-COVID-19 project, Europe, December 2020 to May 2021
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We measured COVID-19 vaccine effectiveness (VE) against symptomatic SARS-CoV-2 infection at primary care/outpatient level among adults ≥ 65 years old using a multicentre test-negative design in eight European countries. We included 592 SARS-CoV-2 cases and 4,372 test-negative controls in the main analysis. The VE was 62% (95% CI: 45-74) for one dose only and 89% (95% CI: 79-94) for complete vaccination. COVID-19 vaccines provide good protection against COVID-19 presentation at primary care/outpatient level, particularly among fully vaccinated individuals.
Kissling , E , Hooiveld , M , Sandonis Martín , V , Martínez-Baz , I , William , N , Vilcu , A M , Mazagatos , C , Domegan , L , de Lusignan , S , Meijer , A , Machado , A , Brytting , M , Casado , I , Murray , J L K , Belhillil , S , Larrauri , A , O'Donnell , J , Tsang , R , de Lange , M , Rodrigues , A P , Riess , M , Castilla , J , Hamilton , M , Falchi , A , Pozo , F , Dunford , L , Cogdale , J , Jansen , T , Guiomar , R , Enkirch , T , Burgui , C , Sigerson , D , Blanchon , T , Martínez Ochoa , E M , Connell , J , Ellis , J , van Gageldonk-Lafeber , R , Kislaya , I , Rose , A MC , Valenciano , M & I-MOVE-COVID-19 primary care study team 2021 , ' Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care : I-MOVE-COVID-19 project, Europe, December 2020 to May 2021 ' , Eurosurveillance , vol. 26 , no. 29 , 2100670 . https://doi.org/10.2807/1560-7917.ES.2021.26.29.2100670
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DescriptionThis project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673.
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