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Challenges in predicting the change in the cumulative exposure of new tobacco and related products based on emissions and toxicity dose–response data
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dc.contributor.author | Staal, Yvonne C. M. | |
dc.contributor.author | Bil, Wieneke | |
dc.contributor.author | Bokkers, Bas G. H. | |
dc.contributor.author | Soeteman-Hernández, Lya G. | |
dc.contributor.author | Stephens, W. Edryd | |
dc.contributor.author | Talhout, Reinskje | |
dc.date.accessioned | 2022-08-24T10:30:14Z | |
dc.date.available | 2022-08-24T10:30:14Z | |
dc.date.issued | 2022-08-24 | |
dc.identifier | 281008249 | |
dc.identifier | 29cdc980-a068-4b4d-9f1e-dc2d433ef8d1 | |
dc.identifier | 000851183900001 | |
dc.identifier | 85137568129 | |
dc.identifier.citation | Staal , Y C M , Bil , W , Bokkers , B G H , Soeteman-Hernández , L G , Stephens , W E & Talhout , R 2022 , ' Challenges in predicting the change in the cumulative exposure of new tobacco and related products based on emissions and toxicity dose–response data ' , International Journal of Environmental Research and Public Health , vol. 19 , no. 17 , 10528 . https://doi.org/10.3390/ijerph191710528 | en |
dc.identifier.issn | 1660-4601 | |
dc.identifier.other | Bibtex: ijerph191710528 | |
dc.identifier.other | ORCID: /0000-0002-0884-8722/work/117997507 | |
dc.identifier.uri | https://hdl.handle.net/10023/25884 | |
dc.description | Funding: This work was funded by the Netherlands Food and Consumer Product Safety Authority (NVWA), Utrecht, the Netherlands. Project number 9.7.1 | en |
dc.description.abstract | Many novel tobacco products have been developed in recent years. Although many may emit lower levels of several toxicants, their risk in the long term remains unclear. We previously published a method for the exposure assessment of mixtures that can be used to compare the changes in cumulative exposure to carcinogens among tobacco products. While further developing this method by including more carcinogens or to explore its application to non-cancer endpoints, we encountered a lack of data that are required for better-substantiated conclusions regarding differences in exposure between products. In this special communication, we argue the case for more data on adverse health effects, as well as more data on the composition of the emissions from tobacco products. Such information can be used to identify significant changes in relevance to health using the cumulative exposure method with different products and to substantiate regulatory decisions. | |
dc.format.extent | 15 | |
dc.format.extent | 944926 | |
dc.language.iso | eng | |
dc.relation.ispartof | International Journal of Environmental Research and Public Health | en |
dc.subject | Tobacco products | en |
dc.subject | Carcinogenicity | en |
dc.subject | Cardiovascular diseases | en |
dc.subject | Heated tobacco | en |
dc.subject | Cumulative exposure | en |
dc.subject | Relative potency | en |
dc.subject | GE Environmental Sciences | en |
dc.subject | RA0421 Public health. Hygiene. Preventive Medicine | en |
dc.subject | DAS | en |
dc.subject | SDG 3 - Good Health and Well-being | en |
dc.subject | MCC | en |
dc.subject.lcc | GE | en |
dc.subject.lcc | RA0421 | en |
dc.title | Challenges in predicting the change in the cumulative exposure of new tobacco and related products based on emissions and toxicity dose–response data | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. School of Earth & Environmental Sciences | en |
dc.identifier.doi | https://doi.org/10.3390/ijerph191710528 | |
dc.description.status | Peer reviewed | en |
dc.identifier.url | https://www.mdpi.com/1660-4601/19/17/10528 | en |
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