St Andrews Research Repository

St Andrews University Home
View Item 
  •   St Andrews Research Repository
  • University of St Andrews Research
  • University of St Andrews Research
  • University of St Andrews Research
  • View Item
  •   St Andrews Research Repository
  • University of St Andrews Research
  • University of St Andrews Research
  • University of St Andrews Research
  • View Item
  •   St Andrews Research Repository
  • University of St Andrews Research
  • University of St Andrews Research
  • University of St Andrews Research
  • View Item
  • Register / Login
JavaScript is disabled for your browser. Some features of this site may not work without it.

Detection and quantification of viable Mycobacterium tuberculosis bacilli in saline-processed stool samples by Tuberculosis Molecular Bacterial Load Assay : a potential alternative for processing stool

Thumbnail
View/Open
Musisi_2022_Detection_and_quantification_Spectrum_00274_22_CCBY.pdf (144.6Kb)
Date
12/05/2022
Author
Musisi, Emmanuel
Ssesolo, Abdul
Sloan, Derek J.
Gillespie, Stephen H.
Sabiiti, Wilber
Keywords
Diagnosis
Mycobacterium tuberculosis
Phosphate-buffered saline
RNA
Tuberculosis
Tuberculosis bacterial load assay
Viable bacillary load
QR Microbiology
E-DAS
SDG 3 - Good Health and Well-being
Metadata
Show full item record
Citation
Musisi , E , Ssesolo , A , Sloan , D J , Gillespie , S H & Sabiiti , W 2022 , ' Detection and quantification of viable Mycobacterium tuberculosis bacilli in saline-processed stool samples by Tuberculosis Molecular Bacterial Load Assay : a potential alternative for processing stool ' , Microbiology Spectrum , vol. 10 , no. 3 , 00274-22 . https://doi.org/10.1128/spectrum.00274-22
Publication
Microbiology Spectrum
Status
Peer reviewed
DOI
https://doi.org/10.1128/spectrum.00274-22
ISSN
2165-0497
Type
Journal item
Rights
Copyright © 2022 Musisi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Description
Funding: Funding from European Developing Clinical Trials Partnership through PanACEA II Consortium (grant TRIA2015-1102), University of St Andrews St Leonards scholarship, Scottish Funding Council-Global Challenges Research Fund, Infectious Diseases Institute Makerere University, Lung MicroCHIP (NIH grant U01 HL098964) and K24 (NIH grant K24 HL087713) is acknowledged.
Collections
  • University of St Andrews Research
URI
http://hdl.handle.net/10023/25839

Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

Related items

Showing items related by title, author, creator and subject.

  • High Mycobacterium tuberculosis bacillary loads detected by tuberculosis molecular bacterial load assay in patient stool : a potential alternative for nonsputum diagnosis and treatment response monitoring of tuberculosis 

    Musisi, Emmanuel; Sessolo, Abdul; Kaswabuli, Sylvia; Zawedde, Josephine; Byanyima, Patrick; Kasiinga, Shariifah; Sanyu, Ingvar; Uwimaana, Esther; Walimbwa, Stanley; Ola, Joseph; Ssengooba, Willy; Sekaggya, Christine; Joloba, Moses L.; Worodria, William; Huang, Laurence; Gillespie, Stephen Henry; Sloan, Derek James; Sabiiti, Wilber (2022-02-23) - Journal article
    Not all patients produce sputum, yet most available TB tests use sputum. We investigated the utility of a novel RNA-based quantitative test, the tuberculosis molecular bacterial load assay (TB-MBLA), for the detection and ...
  • Evaluation of the tuberculosis-molecular bacterial load assay for tuberculosis diagnosis and monitoring response to standard anti-tuberculosis therapy 

    Musisi, Emmanuel (University of St Andrews, 2023-06-16) - Thesis
    Tuberculosis (TB) is a difficult disease to treat, requiring a minimum of six months on a combination of four antibiotics. This thesis reports the first systematic evaluation of the St Andrews' developed RNA-based ...
  • Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis 

    Mzinza, David T.; Sloan, Derek James; Jambo, Kondwani C.; Shani, Doris; Kamdolozi, Mercy; Wilkinson, Katalin A.; Wilkinson, Robert J.; Davies, Geraint R.; Heyderman, Robert S.; Mwandumba, Henry C. (2015-07-01) - Journal article
    In HIV-uninfected adults with pulmonary tuberculosis (TB), anti-TB treatment is associated with changes in Mycobacterium tuberculosis (Mtb)-specific immune responses, which correlate with sputum bacillary load. It is unclear ...
Advanced Search

Browse

All of RepositoryCommunities & CollectionsBy Issue DateNamesTitlesSubjectsClassificationTypeFunderThis CollectionBy Issue DateNamesTitlesSubjectsClassificationTypeFunder

My Account

Login

Open Access

To find out how you can benefit from open access to research, see our library web pages and Open Access blog. For open access help contact: openaccess@st-andrews.ac.uk.

Accessibility

Read our Accessibility statement.

How to submit research papers

The full text of research papers can be submitted to the repository via Pure, the University's research information system. For help see our guide: How to deposit in Pure.

Electronic thesis deposit

Help with deposit.

Repository help

For repository help contact: Digital-Repository@st-andrews.ac.uk.

Give Feedback

Cookie policy

This site may use cookies. Please see Terms and Conditions.

Usage statistics

COUNTER-compliant statistics on downloads from the repository are available from the IRUS-UK Service. Contact us for information.

© University of St Andrews Library

University of St Andrews is a charity registered in Scotland, No SC013532.

  • Facebook
  • Twitter