Show simple item record

Files in this item


Item metadata

dc.contributor.authorHitchcock, Thomas
dc.contributor.authorGardner, Andy
dc.identifier.citationHitchcock , T & Gardner , A 2021 , ' Sex-biased demography modulates male harm across the genome ' , Proceedings of the Royal Society of London Series B: Biological Sciences , vol. 288 , no. 1965 , 20212237 .
dc.descriptionFunding: T.J.H. is supported by a PhD scholarship funded by the School of Biology, University of St Andrews. A.G. is supported by a Natural Environment Research Council Independent Research Fellowship (grant no. NE/K009524/1) and a European Research Council Consolidator (grant no. 771387).en
dc.description.abstractRecent years have seen an explosion of theoretical and empirical interest in the role that kin selection plays in shaping patterns of sexual conflict, with a particular focus on male harming traits. However, this work has focused solely on autosomal genes, and as such it remains unclear how demography modulates the evolution of male harm loci occurring in other portions of the genome, such as sex chromosomes and cytoplasmic elements. To investigate this, we extend existing models of sexual conflict for application to these different modes of inheritance. We first analyse the general case, revealing how sex-specific relatedness, reproductive value and the intensity of local competition combine to determine the potential for male harm. We then analyse a series of demographically explicit models, to assess how dispersal, overlapping generations, reproductive skew and the mechanism of population regulation affect sexual conflict across the genome, and drive conflict between nuclear and cytoplasmic genes. We then explore the effects of sex biases in these demographic parameters, showing how they may drive further conflicts between autosomes and sex chromosomes. Finally, we outline how different crossing schemes may be used to identify signatures of these intragenomic conflicts.
dc.relation.ispartofProceedings of the Royal Society of London Series B: Biological Sciencesen
dc.subjectCytoplasmic inheritanceen
dc.subjectIntragenomic conflicten
dc.subjectOverlapping generationsen
dc.subjectSex chromosomeen
dc.subjectSexual conflicten
dc.subjectSoft selectionen
dc.subjectQH301 Biologyen
dc.subjectQH426 Geneticsen
dc.titleSex-biased demography modulates male harm across the genomeen
dc.typeJournal articleen
dc.contributor.sponsorEuropean Research Councilen
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.contributor.institutionUniversity of St Andrews. Centre for Biological Diversityen
dc.contributor.institutionUniversity of St Andrews. St Andrews Bioinformatics Uniten
dc.description.statusPeer revieweden

This item appears in the following Collection(s)

Show simple item record