Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts
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A new catalytic strategy for the one-pot synthesis of N-sulfonylamidines is described. The cationic copper(I) complexes were found to be highly active and efficient under mild conditions in air and in the absence of solvent. A copper acetylide is proposed as key intermediate in this transformation.
Lazreg , F , Vasseur , M , Slawin , A M Z & Cazin , C S J 2020 , ' Aerobic synthesis of N -sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts ' , Beilstein Journal of Organic Chemistry , vol. 16 , pp. 482-491 . https://doi.org/10.3762/bjoc.16.43
Beilstein Journal of Organic Chemistry
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DescriptionThe authors gratefully acknowledge the EPSRC National Mass Spectroscopy Facilities for the HMRS analysis at the University of Swansea.